tag:blogger.com,1999:blog-64053257095673359682024-03-14T04:58:17.524+01:00Bee Healthy Farms"learning and sharing to bee healthy with products from the beehive"BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.comBlogger382125tag:blogger.com,1999:blog-6405325709567335968.post-59446809884733960462022-02-13T16:20:00.000+01:002022-02-13T16:20:33.384+01:00Propolis Alleviates Depressive Symptoms<p><b><i><span style="color: #800180;">Propolis, rich in numerous polyphenols with unique therapeutic values makes this bee product the most researched worldwide. This randomized placebo-controlled clinical study of Azerbaijan propolis proved it to be an important adjuvant therapeutic with impressive results. Interestingly enough, this anti-depressive characteristic has been identified in previous studies.</span></i></b></p><p><b style="font-size: x-large;">Propolis add-on therapy alleviates depressive symptoms; A randomized placebo-controlled clinical trial</b></p><div style="text-align: left;"><span class="fontstyle0"><span style="font-size: xx-small;"><a href="https://onlinelibrary.wiley.com/doi/10.1002/ptr.7380" target="_blank">J Phytotherapy Research, 24 Jan 2022</a></span></span></div><p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://onlinelibrary.wiley.com/doi/10.1002/ptr.7380" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em; text-align: left;" target="_blank"><img border="0" data-original-height="150" data-original-width="114" height="150" src="https://blogger.googleusercontent.com/img/a/AVvXsEhVKrhbsLYPhSIf-nqfX3Nr4lNGz0UwoXpOUBm_fousIyW1Tx-IRZ6YyUDpf4ziWc47GLBt2zfeoqOM5hFX0caz4lwDW5DDOHyFAajSNu_lwfoiV8NwE2J1XSdVovkNtsJYfSGAQF_2MWuDoWZzQCFPEu5AhzY9Os0_zK06r2Khk7QbBIPMApoX7fq1" width="114" /> </a><a href="https://blogger.googleusercontent.com/img/a/AVvXsEhVKrhbsLYPhSIf-nqfX3Nr4lNGz0UwoXpOUBm_fousIyW1Tx-IRZ6YyUDpf4ziWc47GLBt2zfeoqOM5hFX0caz4lwDW5DDOHyFAajSNu_lwfoiV8NwE2J1XSdVovkNtsJYfSGAQF_2MWuDoWZzQCFPEu5AhzY9Os0_zK06r2Khk7QbBIPMApoX7fq1=s150" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em; text-align: left;"><br /></a><span style="font-family: Calibri, sans-serif; line-height: 107%;"><div style="text-align: left;">Almost
half of the treatments with common antidepressants are failed or result in a
relapse of symptoms after cessation. Moreover, the antidepressants side effects
rationalize the use of complementary medicine as an adjunctive therapy. This
study aimed to <span style="background-color: #fcff01;">evaluate the efficacy and safety of propolis in complementary
therapy of depressive disorder</span>. Chromatography technics were used to detect
propolis components. A double-blind, randomized, placebo-controlled trial was
designed, and 54 participants were randomly assigned to receive either propolis
or Placebo for 6 weeks. Treatment was defined as a decrease in 17-item Hamilton
Depression Scale (HAMD-17) and Beck depression inventory (BDI). On D42, there<br />
was a significant reduction in HAMD score in the propolis group compared with
the placebo group (p < .0001). HAMD score significantly decreased in the
propolis group from 20.92 ± 3.77 on D0 to 10.03 ± 5.55 on D42, and BDI score
was improved from 29.25 ± 3.06 on D0 to 14.17 ± 4.86 on D42. Our findings
confirmed that complementary treatment of propolis with SSRIs could safely
attenuate symptoms of moderate–severe MDD. These <span style="background-color: #fcff01;">antidepressant effects might
result from the rich phenolic acids and flavonoids content of Azerbaijan
propolis</span>.</div><div style="text-align: left;"><br /><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/a/AVvXsEhzDI2b_lyxwb7KGdtGWYUqDGGbBKNNePQ2tvhKcH99oT__rABa3GeyQStBuipT7LEeyVLBVotMdatyOvGYcF3dVDTWVZI4IOi-PmoU05BUECDMK2_QhnCG5ajfTjFtT951cubJxuTjaLNtR3dx4zPoS21gb8N3IjAkyfkoQ7WMF0mYXtodSuz9Nsw4=s950" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img alt="HAMD Score" border="0" data-original-height="762" data-original-width="950" height="258" src="https://blogger.googleusercontent.com/img/a/AVvXsEhzDI2b_lyxwb7KGdtGWYUqDGGbBKNNePQ2tvhKcH99oT__rABa3GeyQStBuipT7LEeyVLBVotMdatyOvGYcF3dVDTWVZI4IOi-PmoU05BUECDMK2_QhnCG5ajfTjFtT951cubJxuTjaLNtR3dx4zPoS21gb8N3IjAkyfkoQ7WMF0mYXtodSuz9Nsw4=w320-h258" title="Placebo vs Propolis" width="320" /></a></div></div></span><a href="https://blogger.googleusercontent.com/img/a/AVvXsEhVKrhbsLYPhSIf-nqfX3Nr4lNGz0UwoXpOUBm_fousIyW1Tx-IRZ6YyUDpf4ziWc47GLBt2zfeoqOM5hFX0caz4lwDW5DDOHyFAajSNu_lwfoiV8NwE2J1XSdVovkNtsJYfSGAQF_2MWuDoWZzQCFPEu5AhzY9Os0_zK06r2Khk7QbBIPMApoX7fq1=s150" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><br /></a><a href="https://blogger.googleusercontent.com/img/a/AVvXsEhVKrhbsLYPhSIf-nqfX3Nr4lNGz0UwoXpOUBm_fousIyW1Tx-IRZ6YyUDpf4ziWc47GLBt2zfeoqOM5hFX0caz4lwDW5DDOHyFAajSNu_lwfoiV8NwE2J1XSdVovkNtsJYfSGAQF_2MWuDoWZzQCFPEu5AhzY9Os0_zK06r2Khk7QbBIPMApoX7fq1=s150" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><br /></a><a href="https://blogger.googleusercontent.com/img/a/AVvXsEhVKrhbsLYPhSIf-nqfX3Nr4lNGz0UwoXpOUBm_fousIyW1Tx-IRZ6YyUDpf4ziWc47GLBt2zfeoqOM5hFX0caz4lwDW5DDOHyFAajSNu_lwfoiV8NwE2J1XSdVovkNtsJYfSGAQF_2MWuDoWZzQCFPEu5AhzY9Os0_zK06r2Khk7QbBIPMApoX7fq1=s150" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><br /></a><a href="https://blogger.googleusercontent.com/img/a/AVvXsEhVKrhbsLYPhSIf-nqfX3Nr4lNGz0UwoXpOUBm_fousIyW1Tx-IRZ6YyUDpf4ziWc47GLBt2zfeoqOM5hFX0caz4lwDW5DDOHyFAajSNu_lwfoiV8NwE2J1XSdVovkNtsJYfSGAQF_2MWuDoWZzQCFPEu5AhzY9Os0_zK06r2Khk7QbBIPMApoX7fq1=s150" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><br /></a><a href="https://blogger.googleusercontent.com/img/a/AVvXsEhVKrhbsLYPhSIf-nqfX3Nr4lNGz0UwoXpOUBm_fousIyW1Tx-IRZ6YyUDpf4ziWc47GLBt2zfeoqOM5hFX0caz4lwDW5DDOHyFAajSNu_lwfoiV8NwE2J1XSdVovkNtsJYfSGAQF_2MWuDoWZzQCFPEu5AhzY9Os0_zK06r2Khk7QbBIPMApoX7fq1=s150" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><br /></a></div><p></p>BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com1tag:blogger.com,1999:blog-6405325709567335968.post-31601037387053618892020-10-30T17:43:00.000+01:002020-10-30T17:43:18.134+01:00Propolis Spray Improves Response to Bacterial, Viral Respiratory Infections<p><b><i><span style="color: #800180;">Long appreciated for its benefits towards respiratory ailments, this double-blind study finds propolis effective in quickly resolving bacterial and viral upper respiratory infections, thus preventing more severe health conditions that would require pharmacological treatment. Best of all, this was documented in a randomized, controlled clinical trial, which is especially satisfying for fans of propolis. </span></i></b></p><div class="separator" style="clear: both; text-align: center;"><a href="https://1.bp.blogspot.com/-G9A-R5QssQw/X5wxwOo2VJI/AAAAAAAAYV8/BenwBLLH-gsmcYABJxyY4QVLTm15u7ZLgCLcBGAsYHQ/s200/j_PhytoMedicine.gif" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img alt="Phytomedicine, Volume 80, January 2021, 153368" border="0" data-original-height="200" data-original-width="150" height="200" src="https://1.bp.blogspot.com/-G9A-R5QssQw/X5wxwOo2VJI/AAAAAAAAYV8/BenwBLLH-gsmcYABJxyY4QVLTm15u7ZLgCLcBGAsYHQ/w150-h200/j_PhytoMedicine.gif" title="Propolis improves response to URTI" width="150" /></a></div><br /><p><br /></p><p><br /></p><p><br /></p><p><br /></p><p><br /><br /><br /><span style="font-family: verdana; font-size: xx-small;"><a href="https://www.sciencedirect.com/science/article/pii/S0944711320301999?via%3Dihub#fig0004"><span style="background-color: white;">J Phytomedicine, </span>Volume 80</a>, Jan 2021, 153368</span></p><p class="MsoNormal"><b><span style="font-family: verdana;"><o:p></o:p></span></b></p><p><b><span style="font-family: verdana;">Background</span></b></p><p class="MsoNormal"><span style="font-family: verdana;">The most
common symptoms of mild upper respiratory tract infections (URTIs) are sore
throat, muffled dysphonia, and swelling and redness of the throat, which result
from the inflammation process following acute bacterial or viral infection. </span></p>
<p class="MsoNormal"><span style="font-family: verdana;"></span></p><div class="separator" style="clear: both; text-align: center;"><span style="font-family: verdana;"><a href="https://1.bp.blogspot.com/-ZpXOqJHM1N0/X5w3-ld2Q6I/AAAAAAAAYWM/YY-nh3YEmAU3F97UTHJ9zhUj2Mk7fT2rQCLcBGAsYHQ/s1333/graph_propolis_URTI.jpg" imageanchor="1" style="clear: right; float: right; margin-bottom: 1em; margin-left: 1em;"><img border="0" data-original-height="511" data-original-width="1333" src="https://1.bp.blogspot.com/-ZpXOqJHM1N0/X5w3-ld2Q6I/AAAAAAAAYWM/YY-nh3YEmAU3F97UTHJ9zhUj2Mk7fT2rQCLcBGAsYHQ/s320/graph_propolis_URTI.jpg" width="320" /></a></span></div><span style="font-family: verdana;"><span lang="EN-US"><b>Hypothesis/purpose</b><br /></span>As propolis
is a natural resinous substance traditionally used to maintain oral cavity and
upper respiratory tract health due to its antimicrobial and anti-inflammatory
properties, the aim of this study is to evaluate the efficacy of an oral spray
based on poplar-type propolis extract with a known and standardized polyphenol
content, on the remission of the symptoms associated with mild uncomplicated
URTIs. </span><p></p>
<p class="MsoNormal"><span style="font-family: verdana;"><span lang="EN-US"><b>Study
design</b><br /></span><span lang="EN-US">A
monocentric, randomized, double-blind, placebo-controlled clinical trial was
performed.</span> <br /></span></p>
<p class="MsoNormal"><span style="font-family: verdana;"><span lang="EN-US"><b>Methods</b><br /></span><span lang="EN-US">This study
was conducted in 122 healthy adults who had perceived mild upper respiratory
tract infections. Participants, randomly assigned to receive either propolis
oral spray (N = 58) or placebo (N = 64), underwent four visits (baseline = t0,
after 3 days = t1 and after 5 days = t2 and after a follow-up of 15 days = t3)
in an outpatient setting. Propolis oral spray total polyphenol content was 15
mg/ml. The dosage was 2–4 sprays, corresponding to 12–24 mg of polyphenols,
three times for five days. The duration of the study was 8 weeks.</span></span></p><div class="separator" style="clear: both; text-align: center;"><span style="font-family: verdana;"><a href="https://1.bp.blogspot.com/-QoijEHw_1lk/X5w-IB4UjiI/AAAAAAAAYWY/8zNS7xOd8sY050r7_XedO3GrmYS_O_p9ACLcBGAsYHQ/s1764/graph_propolis_URTI-2.jpg" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img alt="Subjects with symptoms" border="0" data-original-height="1764" data-original-width="1667" height="320" src="https://1.bp.blogspot.com/-QoijEHw_1lk/X5w-IB4UjiI/AAAAAAAAYWY/8zNS7xOd8sY050r7_XedO3GrmYS_O_p9ACLcBGAsYHQ/w302-h320/graph_propolis_URTI-2.jpg" title="Percentage of subjects positive to symptoms" width="302" /></a></span></div><span style="font-family: verdana;"> </span><p></p>
<p class="MsoNormal"><span style="font-family: verdana;"><span lang="EN-US"><b>Results</b><br /></span><span lang="EN-US">After 3
days of treatment, 83% of subjects treated with propolis oral spray had
<br />remission of symptoms, while 72% of subjects in the placebo group had at least
one remaining symptom. After five days, all subjects had recovered from all
symptoms. This means that resolution from mild uncomplicated URTIs took place
two days earlier, instead of taking place in five days as recorded in the
control group. There was no relationship between the ingestion of propolis oral
spray or placebo and adverse reactions.</span> </span></p>
<p class="MsoNormal"><span style="font-family: verdana;"><span lang="EN-US"><b>Conclusion</b><br /></span><span style="background-color: #fcff01;">Propolis
oral spray can be used to improve both bacterial and viral uncomplicated URTI
symptoms in a smaller number of days without the use of pharmacological
treatment, leading to a prompt symptom resolution</span>. </span></p>BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com0tag:blogger.com,1999:blog-6405325709567335968.post-63951790315820313082019-10-26T11:20:00.003+02:002019-10-26T12:40:01.801+02:00Propolis Mouthwash Outperforms Listerine Against Oral Bacteria<div dir="ltr" style="text-align: left;" trbidi="on">
<i><b><span style="color: purple;">In reviewing studies of propolis use in mucous linings of the body, we find it very effective against bacteria and with anti-inflammatory properties, it speeds healing. This study found propolis more effective than Listerine</span></b></i><span style="background-color: white; color: #545454; font-family: "arial" , sans-serif; font-size: 14px;">®</span><i><b><span style="color: purple;"> and CHX at reducing oral bacteria.</span></b></i><br />
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<span lang="EN-US"><span style="font-family: "verdana" , sans-serif;"><b>Evaluation
of Antibacterial Effect of Propolis and its Application in Mouthwash
Production</b><o:p></o:p></span></span></div>
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<span style="font-family: "verdana" , sans-serif; font-size: xx-small;">Nazeri R1,
Ghaiour M2, Abbasi S3.</span></div>
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<span style="font-family: "verdana" , sans-serif;"><span style="font-size: xx-small;"><a href="https://www.ncbi.nlm.nih.gov/pubmed/31608331" target="_blank">FrontDent. 2019 Jan-Feb;16(1):1-12</a></span> </span></div>
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<a href="https://1.bp.blogspot.com/-8cCFMhjKcq8/XbP4DkKGjaI/AAAAAAAAXAs/2LXE6Kp4htMZT0y44G9MIUlv6jlJntJaACLcBGAsYHQ/s1600/blog_frontiers_dentistry.png" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img alt="" border="0" data-original-height="52" data-original-width="355" height="46" src="https://1.bp.blogspot.com/-8cCFMhjKcq8/XbP4DkKGjaI/AAAAAAAAXAs/2LXE6Kp4htMZT0y44G9MIUlv6jlJntJaACLcBGAsYHQ/s320/blog_frontiers_dentistry.png" title="Frontiers in Dentistry" width="320" /></a></div>
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<span lang="EN-US"><span style="font-family: "verdana" , sans-serif;"><u>OBJECTIVES</u>:<o:p></o:p></span></span></div>
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<span lang="EN-US"><span style="font-family: "verdana" , sans-serif;">Our purpose
was to determine the antibacterial properties of propolis and to evaluate its use
as an antibacterial mouthwash with minimal complications.<o:p></o:p></span></span></div>
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<span lang="EN-US"><span style="font-family: "verdana" , sans-serif;"><u>MATERIALS
AND METHODS</u>:<o:p></o:p></span></span></div>
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<span style="font-family: "verdana" , sans-serif;"><span lang="EN-US">In this
experimental laboratory study, an alcoholic propolis extract was prepared. The
minimum inhibitory concentration (MIC) was calculated for four bacterial
species including Staphylococcus aureus (S. aureus), Streptococcus mutans (S.
mutans), Lactobacillus acidophilus (L. acidophilus), and Enterococcus faecalis
(E. faecalis) using agar dilution. According to the MIC, a propolis
antibacterial mouthwash was produced and compared to water, </span></span><br />
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<span style="font-family: "verdana" , sans-serif;"><span lang="EN-US"><a href="https://1.bp.blogspot.com/-506GmD9LhWI/XbQUqgBDG2I/AAAAAAAAXA8/GHmErO37gOk96gCe9ST6BzqqNYfms6tSwCLcBGAsYHQ/s1600/blog_oral_bacterial_cultures.png" imageanchor="1" style="clear: right; float: right; margin-bottom: 1em; margin-left: 1em;"><img border="0" data-original-height="667" data-original-width="454" height="320" src="https://1.bp.blogspot.com/-506GmD9LhWI/XbQUqgBDG2I/AAAAAAAAXA8/GHmErO37gOk96gCe9ST6BzqqNYfms6tSwCLcBGAsYHQ/s320/blog_oral_bacterial_cultures.png" width="217" /></a></span></span></div>
<span style="font-family: "verdana" , sans-serif;"><span lang="EN-US">chlorhexidine
(CHX), and Listerine</span></span><span style="background-color: white; color: #545454; font-family: "arial" , sans-serif; font-size: 14px;">®</span><span lang="EN-US" style="font-family: "verdana" , sans-serif;"> using laboratory rats for clinical examination. Salivary
specimens of rats were collected at 12 hours, 1 week, and 2 weeks after using
the mouthwash and examined by real-time polymerase chain reaction (RT-PCR).
Data were analyzed using one-way analysis of variance (ANOVA) and repeated
measures ANOVA (</span><span style="font-family: "verdana" , sans-serif;">α</span><span lang="EN-US" style="font-family: "verdana" , sans-serif;">=0.05).</span></div>
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<span lang="EN-US"><span style="font-family: "verdana" , sans-serif;"><u>RESULTS</u>:<o:p></o:p></span></span></div>
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<span lang="EN-US" style="line-height: 107%;"><span style="font-family: "verdana" , sans-serif;">The results of agar dilution test showed the lowest MIC for Staphylococcus aureus and the highest for Lactobacillus acidophilus. On the other hand, the results of this study showed that water alone had no effect on the level of oral bacteria. In the case of Streptococcus mutans, Enterococcus faecalis, and Lactobacillus Acidophilus mouthwash, the <span style="background-color: yellow;">Propolis mouthwash showed a significant difference with chlorhexidine and Listerine (P < 0 .05) , while chlorhexidine and listerine had lower effect in comparison</span>. As for Staphylococcus aureus, there was no significant difference between chlorhexidine and listerine (P > 0 .05), but Listerine had the lower
effect than either (P < 0 .05 ) but Listerine had the lower effect than either ( P < 0.05 ).
</span></span></div>
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<span lang="EN-US"><o:p></o:p></span></div>
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<span lang="EN-US"><span style="font-family: "verdana" , sans-serif;"><u>CONCLUSION</u>:<o:p></o:p></span></span></div>
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<span lang="EN-US"><span style="font-family: "verdana" , sans-serif;">According
to the results, <span style="background-color: yellow;">propolis mouthwash was more efficient against the studied oral
bacteria compared to CHX and Listerine</span></span></span><span style="background-color: yellow; color: #545454; font-family: "arial" , sans-serif; font-size: 14px;">®</span><span style="font-family: "verdana" , sans-serif;">.</span></div>
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<span lang="EN-US" style="line-height: 107%;"><span style="font-family: "verdana" , sans-serif; font-size: xx-small;">Copyright© Dental Research Center, Tehran
University of Medical Sciences.</span></span><br />
<br /></div>
BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com0tag:blogger.com,1999:blog-6405325709567335968.post-74576539873938352762018-05-24T22:26:00.000+02:002018-05-24T22:26:59.484+02:00Honey: A Healthy Choice for Diabetics<div dir="ltr" style="text-align: left;" trbidi="on">
<i><b><span style="color: purple;">This published article reviews all studies that validate honey as a novel anti-diabetic agent. To no surprise, honey has been revered as a naturally, preferred sweetner for diabetics, simp</span></b></i><i><b><span style="color: purple;">ly for the fact that it doesn't require insulin to be digested. This peer-reviewed article from Romanian</span></b></i><i><b><span style="color: purple;"> faculty is very qualified to digest the data for the intrinsic value contained within.</span></b></i><br />
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<span lang="EN-GB"><span style="font-family: "verdana" , sans-serif;"><b>Honey and
Diabetes: The Importance of Natural Simple Sugars in Diet for Preventing and
Treating Different Type of Diabetes</b><o:p></o:p></span></span></div>
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<a href="https://1.bp.blogspot.com/-D1KIIJT0g4M/T0Qdb4DVoAI/AAAAAAAACUE/laQFK5VdD00s_zo4i-U1VL9uYB2mgiOjQCPcBGAYYCw/s1600/blog_oxid_medicine.jpg" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img border="0" data-original-height="226" data-original-width="170" height="200" src="https://1.bp.blogspot.com/-D1KIIJT0g4M/T0Qdb4DVoAI/AAAAAAAACUE/laQFK5VdD00s_zo4i-U1VL9uYB2mgiOjQCPcBGAYYCw/s200/blog_oxid_medicine.jpg" width="150" /></a></div>
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<span lang="EN-GB"><span style="font-family: "verdana" , sans-serif; font-size: xx-small;"><a href="https://www.hindawi.com/journals/omcl/2018/4757893/" target="_blank">Oxid MedCell Longev. 2018 Feb 4;2018:4757893</a></span></span></div>
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<span lang="EN-GB"><span style="font-family: "verdana" , sans-serif;">Diabetes is
a metabolic disorder with multifactorial and heterogeneous etiologies. Two
types of diabetes are common among humans: type 1 diabetes that occurs when the
immune system attacks and destroys insulin and type 2 diabetes, the most common
form, that may be caused by several factors, the most important being
lifestyle, but also may be determined by different genes.<o:p></o:p></span></span></div>
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<span lang="EN-GB"><span style="font-family: "verdana" , sans-serif;">Honey was
used in folk medicine for a long time, but the health benefits were explained
in the last decades, when the scientific world was concerned in testing and
thus explaining the benefits of honey.</span></span></div>
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<span style="font-family: "verdana" , sans-serif;"><a href="https://4.bp.blogspot.com/-uLPF-HuPlU0/WrFgqytvQQI/AAAAAAAAQiE/DE6kL8L79u092x43a-7gGGBe1NjKf5RQACLcBGAs/s1600/blog_j_graph_honey_vs_sugar.jpg" imageanchor="1" style="clear: right; float: right; margin-bottom: 1em; margin-left: 1em;"><img border="0" data-original-height="700" data-original-width="566" height="320" src="https://4.bp.blogspot.com/-uLPF-HuPlU0/WrFgqytvQQI/AAAAAAAAQiE/DE6kL8L79u092x43a-7gGGBe1NjKf5RQACLcBGAs/s320/blog_j_graph_honey_vs_sugar.jpg" width="258" /></a></span></div>
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<span lang="EN-GB"><span style="font-family: "verdana" , sans-serif;">Different
studies demonstrate the hypoglycemic effect of honey, but the mechanism of this
effect remains unclear.<o:p></o:p></span></span></div>
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<span lang="EN-GB"><span style="font-family: "verdana" , sans-serif;"><span style="background-color: yellow;">This review
presents the experimental studies completed in the recent years, which support
honey as a novel antidiabetic agent</span> that might be of potential significance for
the management of diabetes and its complications and also highlights the
potential impacts and future perspectives on the use of honey as an
antidiabetic agent.<o:p></o:p></span></span></div>
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<span lang="EN-GB"><span style="font-family: "verdana" , sans-serif;"><span style="font-size: x-small;">Download the complete article here</span>.</span></span></div>
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BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com5tag:blogger.com,1999:blog-6405325709567335968.post-65907896090796931232018-04-27T17:15:00.002+02:002019-03-01T10:32:37.449+01:00Propolis: A Natural Healer of Gastrointestinal Diseases<div dir="ltr" style="text-align: left;" trbidi="on">
<b><span style="color: purple;"><i>Propolis heals and protects - both in the hive and within living beings. Previous studies also confirm the effectiveness of its therapeutic properties on mucous linings of the body. Not surprising that its anti-inflammatory effects on gastrointestinal diseases.</i></span></b><br />
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<span lang="EN-GB" style="mso-ansi-language: EN-GB;"><span style="font-family: "verdana" , sans-serif;"><b>Propolis:
The future therapy against Helicobacter pylori-mediated gastrointestinal
diseases</b><o:p></o:p></span></span></div>
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<span lang="EN-GB" style="mso-ansi-language: EN-GB;"><b><span style="font-family: "verdana" , sans-serif; font-size: xx-small;"><a href="https://www.sciencedirect.com/science/article/pii/S1214021X16302964" target="_blank">Journal Applied Biomedicine; Vol 6, issue 2; May 2018</a></span></b></span></div>
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<a href="https://3.bp.blogspot.com/-vjiO7pbqjKI/WuD3Iff94xI/AAAAAAAARXU/_Xcj691g_UYl8gMoBe6N385WjSV8HCr9wCLcBGAs/s1600/blog_j_applied_biomedicine.gif" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img alt="Journal of Applied Biomedicine" border="0" data-original-height="150" data-original-width="109" height="200" src="https://3.bp.blogspot.com/-vjiO7pbqjKI/WuD3Iff94xI/AAAAAAAARXU/_Xcj691g_UYl8gMoBe6N385WjSV8HCr9wCLcBGAs/s200/blog_j_applied_biomedicine.gif" title="Journal of Applied Biomedicine" width="145" /></a><span lang="EN-GB" style="mso-ansi-language: EN-GB;"><span style="font-family: "verdana" , sans-serif;"><u><b>Abstract:</b></u><o:p></o:p></span></span></div>
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<span lang="EN-GB" style="mso-ansi-language: EN-GB;"><span style="font-family: "verdana" , sans-serif;">Helicobacter
pylori (H. pylori), which is found in the stomach of approximately 50% of
humans, remains there for almost the entire lifetime </span></span><span style="font-family: "verdana" , sans-serif;">of the infected
individual, leading to various gastrointestinal tract-associated disorders
following full-blown infection. </span></div>
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<span lang="EN-GB" style="mso-ansi-language: EN-GB;"><span style="font-family: "verdana" , sans-serif;">Due to the emergence of antibiotic resistance,
recurrence and high cost of therapy, most antibiotic-based treatment strategies
are not very effective in eradicating H. pylori infections. The quest for an
alternative treatment free of these inconveniences is currently in demand. One
of the important alternatives is <span style="background-color: yellow;">propolis</span>, produced by the honeybee Apis
mellifera, which has been used to treat different diseases since it <span style="background-color: yellow;">possesses a
wide range of biochemical properties</span>.</span></span></div>
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<a href="https://2.bp.blogspot.com/-mmYMczdkSrg/WuD2x6s_API/AAAAAAAARXM/ZhLTPnFIBLYUtP_ab-JBfydj6fs44lYqwCLcBGAs/s1600/blog_graph_propolis_heliobactepylori.jpg" imageanchor="1" style="clear: right; float: right; margin-bottom: 1em; margin-left: 1em;"><span style="font-family: "verdana" , sans-serif;"><img border="0" data-original-height="245" data-original-width="237" src="https://2.bp.blogspot.com/-mmYMczdkSrg/WuD2x6s_API/AAAAAAAARXM/ZhLTPnFIBLYUtP_ab-JBfydj6fs44lYqwCLcBGAs/s1600/blog_graph_propolis_heliobactepylori.jpg" /></span></a></div>
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<span lang="EN-GB" style="mso-ansi-language: EN-GB;"><span style="font-family: "verdana" , sans-serif;">Propolis has been reported <span style="background-color: yellow;">as a useful therapeutic
regimen against H. pylori</span>, which is an important cause of gastric inflammation,
peptic ulcer, gastric cancer, and lymphomas of mucosa-associated lymphoid
tissues. Apart from propolis, various active compounds of other natural
products have also been confirmed to be effective. This review compiles the
<span style="background-color: yellow;">scientific evidence of the role of propolis</span> and other natural products against
H. pylori-associated gastrointestinal tract-related health complexities by
acting <span style="background-color: yellow;">as an anti-angiogenic, anti-inflammatory, and antioxidant factor as well
as via modulation of enzymatic activities</span>.<o:p></o:p></span></span></div>
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BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com1tag:blogger.com,1999:blog-6405325709567335968.post-38743467207231550722018-03-15T10:54:00.000+01:002018-03-15T10:54:05.357+01:00Propolis: Potential Solution to Gluten-induced Celiac Disease<div dir="ltr" style="text-align: left;" trbidi="on">
<i><b><span style="color: purple;">The anti-inflammatory effects of propolis are well-documented, especially on mucous linings of the body. This study reaffirms its capacity to reduce inflammation while also diminishing nitric oxide synthase, another inflammatory factor in septic shock, auto-immune diseases or proinflammatory cytokine production.</span></b></i><div>
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<span lang="EN-GB"><span style="font-family: Verdana, sans-serif;"><b>Ex vivo
immunomodulatory effect of ethanolic extract of propolis during Celiac Disease:
involvement of nitric oxide pathway</b><o:p></o:p></span></span></div>
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<span lang="EN-GB"><span style="font-family: Verdana, sans-serif;"><span style="font-size: xx-small;"><a href="https://link.springer.com/article/10.1007/s10787-018-0460-6">Inflammopharmacology.2018 Mar 7</a> </span><o:p></o:p></span></span></div>
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<a href="https://1.bp.blogspot.com/-hAZ1_otYnAA/WqmS9F2WpeI/AAAAAAAAQXQ/-zHeueWeulQ4qpoPHubWs2JZg8fxUrFkwCLcBGAs/s1600/blog_j_inflammo_pharma.jpg" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img border="0" data-original-height="203" data-original-width="153" src="https://1.bp.blogspot.com/-hAZ1_otYnAA/WqmS9F2WpeI/AAAAAAAAQXQ/-zHeueWeulQ4qpoPHubWs2JZg8fxUrFkwCLcBGAs/s1600/blog_j_inflammo_pharma.jpg" /></a></div>
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<span lang="EN-GB" style="mso-ansi-language: EN-GB;"><span style="font-family: Verdana, sans-serif;">Celiac
Disease (CeD) is a chronic immune-mediated enteropathy, in which dietary gluten
induces an inflammatory reaction, predominantly in the duodenum. Propolis is a
resinous hive product, collected by honeybees from various plant sources.<o:p></o:p></span></span></div>
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<span lang="EN-GB" style="mso-ansi-language: EN-GB;"><span style="font-family: Verdana, sans-serif;">Propolis is
well-known for its anti-inflammatory, anti-oxidant and immunomodulatory
effects, due to its major compounds, polyphenols and flavonoids. The aim of our
study was to assess the ex vivo effect of ethanolic extract of propolis (EEP)
upon the activity and expression of iNOS, along with IFN-γ and IL-10 production
in Algerian Celiac patients. In this context, PBMCs isolated from peripheral
blood of Celiac patients and healthy controls were cultured with different
concentrations of EEP. NO production was measured using the Griess method,
whereas quantitation of IFN-γ and IL-10 levels was performed by ELISA.
Inducible nitric oxide synthase (iNOS) expression, NFκB and pSTAT-3 activity
were analyzed by immunofluorescence assay.<o:p></o:p></span></span></div>
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<span lang="EN-GB" style="mso-ansi-language: EN-GB;"><span style="font-family: Verdana, sans-serif;">Our results
showed that PBMCs from Celiac patients produced high levels of NO and IFN-γ
compared with healthy controls (HC). Interestingly, <span style="background-color: yellow;">EEP reduced significantly,
NO and IFN-γ levels</span> and significantly increased IL-10 levels at a concentration
of 50 µg/mL. Importantly, <span style="background-color: yellow;">EEP downmodulated the iNOS expression</span> as well as the
<span style="background-color: yellow;">activity of NFκB and pSTAT-3</span> transcription factors.<o:p></o:p></span></span></div>
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<a href="https://2.bp.blogspot.com/-t3zlsGHrQNY/Wqo6VmGBnNI/AAAAAAAAQXk/8pcDLDTYSJMeFpi6qtQMmK4Ib8PlWsdGgCLcBGAs/s1600/dreamstime_s_41508355.jpg" imageanchor="1" style="clear: right; float: right; margin-bottom: 1em; margin-left: 1em;"><img border="0" data-original-height="360" data-original-width="800" height="144" src="https://2.bp.blogspot.com/-t3zlsGHrQNY/Wqo6VmGBnNI/AAAAAAAAQXk/8pcDLDTYSJMeFpi6qtQMmK4Ib8PlWsdGgCLcBGAs/s320/dreamstime_s_41508355.jpg" width="320" /></a></div>
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<span lang="EN-GB" style="mso-ansi-language: EN-GB;"><span style="font-family: Verdana, sans-serif;">Altogether,
our results highlight the immunomodulatory effect of propolis on NO pathway and
on pro-inflammatory cytokines. Therefore, we suggest that <span style="background-color: yellow;">propolis may
constitute a potential candidate to modulate inflammation during Celiac Disease
and has a potential therapeutic value</span>.<o:p></o:p></span></span></div>
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BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com1tag:blogger.com,1999:blog-6405325709567335968.post-17434974044004608242017-10-29T22:00:00.000+01:002017-10-29T22:08:52.743+01:00Functional Food for Better Health - Honey, Propolis & Royal Jelly<div dir="ltr" style="text-align: left;" trbidi="on">
<b><i><span style="color: purple;">Its all in the ingredients!! Each of these products merit healthy respect but all three together? In Apitherapy, that's called Synergistic Power! If you're consuming these bee products, you're not only saving your life but helping bees maintain an important role and contributor to all beings on our planet. </span></i></b><br />
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<span lang="EN-GB" style="font-family: "verdana" , sans-serif;"><b><span style="font-size: large;">Honey,
Propolis, and Royal Jelly: A Comprehensive Review of Their Biological Actions
and Health Benefits</span></b><o:p></o:p></span></div>
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<span lang="EN-GB"><span style="font-family: "verdana" , sans-serif; font-size: xx-small;"><a href="https://www.hindawi.com/journals/omcl/2017/1259510/">JOxidMed</a> 2017 February</span></span></div>
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<a href="https://4.bp.blogspot.com/-5e3ZykaAkxM/TnN94hW2fXI/AAAAAAAACIk/2DxIFqFkYRkUqC0IlwFQhM4iA7JcpHBwwCPcBGAYYCw/s1600/blog_oxid_medicine.jpg" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><span style="font-family: "verdana" , sans-serif;"><img alt="" border="0" data-original-height="226" data-original-width="170" height="200" src="https://4.bp.blogspot.com/-5e3ZykaAkxM/TnN94hW2fXI/AAAAAAAACIk/2DxIFqFkYRkUqC0IlwFQhM4iA7JcpHBwwCPcBGAYYCw/s200/blog_oxid_medicine.jpg" title="Oxidative Medicine and Cellular Longevity" width="150" /></span></a></div>
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<span style="font-family: "verdana" , sans-serif;"><b><u>Introduction</u></b></span><br />
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<span style="font-family: "verdana" , sans-serif;"><span lang="EN-GB">Apiculture
is the science and art of prolonging, sustaining, and retaining health by using
products obtained from honeybee hives, such as honey, bee bread, bee venom, bee
pollen, propolis, and royal jelly. Recent years have seen the fast application
of bee products in both traditional and modern medicine. Currently, <span style="background-color: yellow;">many
studies are targeted toward investigating directed health benefits and
pharmacological </span></span><span lang="EN-GB"><span style="background-color: yellow;">properties
of bee products due to their efficacies</span>, leading to the increasing development
of nutraceuticals and functional food from these products. The concept of
functional food refers to food that has the ability to promote better physiological
or psychological health compared to traditional remediated and nutritional
food. <span style="background-color: yellow;">These effects positively contribute toward excellent health maintenance,
well-being, and reduced chronic illness</span> [1]. The present review focuses on the potential
health benefits of bee products, including honey, </span>propolis, and royal jelly. </span></div>
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<a href="https://4.bp.blogspot.com/-OeBXlukvASQ/WfZA46ybhsI/AAAAAAAANqo/cBjCgMAMB2s2Rc81cVLnxs6Ke3RgcXDwwCLcBGAs/s1600/honey_benefits.jpg" imageanchor="1" style="clear: right; float: right; margin-bottom: 1em; margin-left: 1em;"><img border="0" data-original-height="542" data-original-width="540" height="200" src="https://4.bp.blogspot.com/-OeBXlukvASQ/WfZA46ybhsI/AAAAAAAANqo/cBjCgMAMB2s2Rc81cVLnxs6Ke3RgcXDwwCLcBGAs/s200/honey_benefits.jpg" width="198" /></a></div>
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<span style="font-family: "verdana" , sans-serif;"><b><u>Conclusion</u></b></span><br />
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<span lang="EN-GB"><span style="font-family: "verdana" , sans-serif;">The present
review focused on the potential health benefits of bee products such as honey,
propolis, and royal jelly. <span style="background-color: yellow;">These products are highly rich in active components
such as flavonoids, phenolic acid, phenolic compounds, terpenes, and enzymes,
which have biological functions in preventing some diseases and promoting good
health</span>. Honey, propolis, and royal jelly have distinct efficacies with significant
nutritional properties and functional values. Thus, these bee products can be
developed into potent apitherapeutic agents. However, some precautions need to
be taken in case of allergens associated with bee products and in finding the
right intake dosage. Hence, it is necessary to conduct further studies to determine
the critical mechanisms related to the pharmacological activities of these bee
products and the appropriate amounts that can be taken in order to obtain
promising health benefits.<o:p></o:p></span></span></div>
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BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com17tag:blogger.com,1999:blog-6405325709567335968.post-80826513791202564032017-09-26T17:42:00.001+02:002017-09-26T17:42:26.624+02:00Buckwheat Honey Exhibits Super Protective Effect<div dir="ltr" style="text-align: left;" trbidi="on">
<b><span style="color: purple;"><i>Generally speaking, the darker the honey the richer it is both in mineral content and therapeutic effect. Buckwheat honey has a history of it's beneficial value and this study confirms its high antioxidant activity and phenolic content. Though it may be strong in flavor for the palette, it's an ideal complement to a wound healing strategy.</i></span></b><br />
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<span lang="EN-GB"><span style="font-family: Verdana, sans-serif;"><b>The
Protective Effect of Whole Honey and Phenolic Extract on Oxidative DNA Damage
in Mice Lymphocytes Using Comet Assay</b><o:p></o:p></span></span></div>
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<span style="font-family: Verdana, sans-serif; font-size: xx-small;"><a href="https://link.springer.com/article/10.1007/s11130-017-0634-1" target="_blank">Plant Foods for Human Nutrition</a> 2017 Sep 19</span></div>
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<a href="https://4.bp.blogspot.com/-2aTSliCg2fo/Wcp0EeyJvKI/AAAAAAAAM_4/VNab0nzwMU8qSbhYXuK5IIsluqPqHG66gCLcBGAs/s1600/plants_foods_human_nutrition.jpg" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img border="0" data-original-height="203" data-original-width="153" src="https://4.bp.blogspot.com/-2aTSliCg2fo/Wcp0EeyJvKI/AAAAAAAAM_4/VNab0nzwMU8qSbhYXuK5IIsluqPqHG66gCLcBGAs/s1600/plants_foods_human_nutrition.jpg" /></a></div>
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<span lang="EN-GB"><span style="font-family: Verdana, sans-serif;">In this
study, the antioxidant activity and the protective effect against hydrogen
peroxide-induced DNA damage were assessed for five honeys of different
botanical origin. Seven phenolic acids were detected in the honey samples.
Ferulic acid was the most abundant phenolic acid detected in longan honey,
jujube honey and buckwheat honey. Ellagic acid, p-hydroxybenzoic acid and
protocatechuic acid were the main phenolic acids detected in vitex honey.<o:p></o:p></span></span></div>
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<span lang="EN-GB"><span style="font-family: Verdana, sans-serif;">Of all
honey samples tested, the <span style="background-color: yellow;">highest total phenolic content and antioxidant
activity were found in buckwheat honey</span>, whereas the lowest total phenolic content
and antioxidant activity were found in locust honey. Treatment with hydrogen
peroxide induced a 62% increase in tail DNA in mice lymphocytes, and all
studied honeys significantly inhibited this effect (P < 0.05).<o:p></o:p></span></span></div>
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<span lang="EN-GB"><span style="font-family: Verdana, sans-serif;">The
<span style="background-color: yellow;">buckwheat honey with higher antioxidant capability also exhibited super
protective effect</span> than others. Phenolic extracts of honey displayed greater
protective effects than whole honey in comet assay. The hydrogen
peroxide-generated increase in 8-hydroxy-2-deoxyguanosine (8-OHdG) was effectively
inhibited by the honeys studied (P < 0.05). Moreover, a dose-effect
relationship between honey concentration and its protective effect was clearly
observed in this study.<o:p></o:p></span></span></div>
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<span lang="EN-GB"><span style="font-family: Verdana, sans-serif;">It can be
deduced that <span style="background-color: yellow;">phenolic acids of honey can penetrate into lymphocytes and protect
DNA from oxidative damage</span> by scavenging hydrogen peroxide and/or chelating
ferrous ions.<o:p></o:p></span></span></div>
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BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com1tag:blogger.com,1999:blog-6405325709567335968.post-2522290976804601532016-09-30T15:50:00.000+02:002016-09-30T15:52:24.101+02:00Antimicrobial Effects of Royal Jelly Confirmed<div dir="ltr" style="text-align: left;" trbidi="on">
<b><i><span style="color: purple;">Deserving of its name, Royal Jelly is indeed very remarkable! Not only does it provide hormonal support in men and women, acts as a "brain booster" aiding mental capacities, it also has significant antimicrobial force, especially against Gram positive bacteria. </span></i></b><br />
<br />
<span lang="EN-US" style="font-size: 12pt;"><span style="font-family: "verdana" , sans-serif;"><b>Royal Jelly: An
Ancient Remedy with Remarkable Antibacterial Properties</b></span></span><br />
<span lang="EN-US" style="font-size: 12pt;"><span style="font-family: Verdana, sans-serif; font-size: xx-small;"><span lang="EN-US"><a href="http://linkinghub.elsevier.com/retrieve/pii/S0944-5013(16)30083-0" target="_blank">Microbiol Res</a>. 2016
Nov</span></span></span><br />
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<a href="https://4.bp.blogspot.com/-QRzvZ749csA/V-5sOS1V8SI/AAAAAAAAIiw/TvIa8eMYbk0mjcRdao_LiztftzMTL2m1gCLcB/s1600/blog_micro_biolog_res.gif" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img border="0" src="https://4.bp.blogspot.com/-QRzvZ749csA/V-5sOS1V8SI/AAAAAAAAIiw/TvIa8eMYbk0mjcRdao_LiztftzMTL2m1gCLcB/s1600/blog_micro_biolog_res.gif" /></a></div>
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<span lang="EN-US" style="font-size: 12pt;"><span style="font-family: "verdana" , sans-serif;"><u>Abstract</u></span></span><br />
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<span lang="EN-US"><span style="font-family: "verdana" , sans-serif;">Royal Jelly (RJ), a honeybee hypopharyngeal
gland secretion of young nurse and an exclusive nourishment for bee queen, has
been used since ancient times for care and human health and it is still very
important in traditional and folkloristic medicine, especially in Asia within
the apitherapy.<o:p></o:p></span></span></div>
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<span lang="EN-US"><span style="font-family: "verdana" , sans-serif;">Recently, RJ and its protein and lipid
components have been subjected to several investigations on their antimicrobial
activity due to extensive traditional uses and for a future application in
medicine. Antimicrobial activities of crude Royal Jelly, Royalisin,
10-hydroxy-2-decenoic acid, Jelleines,<o:p></o:p></span></span></div>
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<span lang="EN-US"><span style="font-family: "verdana" , sans-serif;">Major Royal Jelly Proteins against
different bacteria have been reported. All these beehive products showed
antimicrobial activities that lead their potential employment in several fields
as natural additives. <span style="background-color: yellow;">RJ and its derived compounds show a highest activity
especially against Gram positive bacteria</span>. The purpose of this Review is to
summarize the results of antimicrobial studies of Royal Jelly following the
timescale of the researches.<o:p></o:p></span></span></div>
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<span lang="EN-US" style="font-size: 12pt;"><span style="font-family: "verdana" , sans-serif;">From the first scientific applications to the
isolation of the single components in order to better understand its
application in the past years and propose an employment in future studies as a
natural antimicrobial agent.</span></span><br />
<span lang="EN-US" style="font-size: 12pt;"><span style="font-family: "verdana" , sans-serif;"><br /></span></span>
<span lang="EN-US" style="font-family: "times new roman" , serif; font-size: 12.0pt;"><br /></span></div>
BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com5tag:blogger.com,1999:blog-6405325709567335968.post-72864006908614104762016-09-18T21:26:00.000+02:002016-09-18T21:26:05.127+02:00Honey is for Horses and Humans, Heals Wounds<div dir="ltr" style="text-align: left;" trbidi="on">
<b><i><span style="color: purple;">The take-away from this study is that honey heals wounds, certainly raw honey (unheated & unfiltered) which contains Lactic Acid Bacteria. Many studies have demonstrated its healing capacity with regards to wounds but the researchers chose hard-to-heal wounds that took more than a year to heal! The results are very impressive, as antibiotic-resistant strains are becoming more commonplace in medical establishments.</span></i></b><br />
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<span lang="EN-US"><span style="font-family: Verdana, sans-serif;"><b>Fighting Off Wound Pathogens in Horses with
Honeybee Lactic Acid Bacteria</b><o:p></o:p></span></span></div>
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<span lang="EN-US"><span style="font-family: Verdana, sans-serif;"><a href="http://link.springer.com/article/10.1007%2Fs00284-016-1080-2" style="font-size: x-small;" target="_blank">Current Microbiology</a> </span></span><span style="font-family: Verdana, sans-serif; font-size: xx-small;">October 2016</span></div>
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<a href="https://1.bp.blogspot.com/-zFS2Ph_CxnE/V97kVzQXkII/AAAAAAAAIiA/U70egYmf8aEuI_DBXsNyfjmiSeOSUTsLACLcB/s1600/blog_current_microbiology.jpg" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img border="0" src="https://1.bp.blogspot.com/-zFS2Ph_CxnE/V97kVzQXkII/AAAAAAAAIiA/U70egYmf8aEuI_DBXsNyfjmiSeOSUTsLACLcB/s1600/blog_current_microbiology.jpg" /></a></div>
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<span lang="EN-US"><span style="font-family: Verdana, sans-serif;">In the global perspective of antibiotic
resistance, it is urgent to find potent topical antibiotics for the use in
human and animal infection. Healing of equine wounds, particularly in the
limbs, is difficult due to hydrostatic factors and exposure to environmental
contaminants, which can lead to heavy bio-burden/biofilm formation and
sometimes to infection. Therefore, antibiotics are often prescribed. Recent
studies have shown that honeybee-specific lactic acid bacteria (LAB), involved
in honey production, and inhibit human wound pathogens.<o:p></o:p></span></span></div>
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<span lang="EN-US"><span style="font-family: Verdana, sans-serif;">The aim of this pilot study was to
investigate the effects on the <span style="background-color: yellow;">healing of hard-to-heal equine wounds</span> after
treatment with these LAB symbionts viable in a heather honey formulation. For
this, we included ten horses with wound duration of >1 year, investigated
the wound microbiota, and treated wounds with the novel honeybee LAB
formulation. We identified the microbiota using MALDI-TOF mass spectrometry and
DNA sequencing. In addition, the antimicrobial properties of the honeybee LAB
formulation were tested against all wound isolates in vitro.</span></span></div>
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<span style="font-family: Verdana, sans-serif;"><a href="https://1.bp.blogspot.com/-qTkDYKxryeM/V97p8B44sHI/AAAAAAAAIiM/bFyYvIz1fOkbFa829ZjyycDEsssWNpiggCLcB/s1600/blog_clinical_microbiology_bacteria_healing.jpg" imageanchor="1" style="clear: right; float: right; margin-bottom: 1em; margin-left: 1em;"><img border="0" height="196" src="https://1.bp.blogspot.com/-qTkDYKxryeM/V97p8B44sHI/AAAAAAAAIiM/bFyYvIz1fOkbFa829ZjyycDEsssWNpiggCLcB/s320/blog_clinical_microbiology_bacteria_healing.jpg" width="320" /></a></span></div>
<span style="font-family: Verdana, sans-serif;"><o:p></o:p></span><br />
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<span lang="EN-US"><span style="font-family: Verdana, sans-serif;">Our results indicate a diverse wound
microbiota including fifty-three bacterial species that showed 90 %
colonization by at least one species of Staphylococcus. <span style="background-color: yellow;">Treatment with the
formulation promoted wound healing in all cases</span> already after the first
application and the wounds were either completely healed (n = 3) <span style="background-color: yellow;">in less than
20 days</span> or healing was in progress. Furthermore, the honeybee LAB formulation
inhibited all pathogens when tested in vitro.<o:p></o:p></span></span></div>
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<span lang="EN-US"><span style="font-family: Verdana, sans-serif;">Consequently, this new treatment option
presents as <span style="background-color: yellow;">a powerful candidate for the topical treatment of hard-to-heal
wounds</span> in horses. <o:p></o:p></span></span></div>
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<span lang="EN-US"><span style="font-family: Verdana, sans-serif;"><br /></span></span></div>
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<span lang="EN-US"></span></div>
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<span lang="EN-US"><span style="font-family: Verdana, sans-serif;">The rapid, painless healing of hard-to-heal
equine wounds gives us reason to believe that the honeybee LAB formulation
presents a new topical option in future wound healing. This new treatment may
be a stepping-stone toward an alternative solution for treating other infected
wounds in animals and humans and warrants further investigation.</span><o:p></o:p></span></div>
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<span lang="EN-US"><br /></span></div>
</div>
BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com0tag:blogger.com,1999:blog-6405325709567335968.post-41731495897922186412016-08-12T18:07:00.001+02:002019-03-01T10:31:31.249+01:00Chrysin Flavonoid in Honey, Propolis Prevents Cell Damage<div dir="ltr" style="text-align: left;" trbidi="on">
<b><i><span style="color: purple;">Just one of numerous flavonoids found in propolis and in smaller doses in honey, Chrysin has been found to protect cells from lab-induced ammonia intoxication. The protective effects of this flavonoid is a common trait with propolis, where we find it always protecting and healing various conditions as well as preventing damaging effects from chemicals, drugs, pesticides, etc.</span></i></b><br />
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<span style="font-family: "verdana" , sans-serif;"><b><a href="https://www.blogger.com/null" name="OLE_LINK2"></a><span lang="EN-US">Chrysin, a flavonoid attenuates
histological changes of </span><a href="https://www.blogger.com/null" name="OLE_LINK4"></a><span lang="EN-US">hyperammonemic</span></b><span lang="EN-US"><b> rats: A dose dependent study</b><o:p></o:p></span></span></div>
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<span style="font-family: "verdana" , sans-serif; font-size: xx-small;"><a href="http://www.ncbi.nlm.nih.gov/pubmed/27470372" target="_blank">Biomed Pharmacother. 2016</a> May 24;82:345-354</span></div>
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<a href="https://2.bp.blogspot.com/-M_ViCX9AcgI/V63ugUjwahI/AAAAAAAAIgs/q6sP3h_Apr4HTP6M8gGxEfr0jmC3uW_ogCLcB/s1600/blog_j_biomedicine_pharmacotherapy.jpg" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img border="0" src="https://2.bp.blogspot.com/-M_ViCX9AcgI/V63ugUjwahI/AAAAAAAAIgs/q6sP3h_Apr4HTP6M8gGxEfr0jmC3uW_ogCLcB/s1600/blog_j_biomedicine_pharmacotherapy.jpg" /></a></div>
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<span lang="EN-US"><span style="font-family: "verdana" , sans-serif;">Chrysin (5,7-dihydroxyflavone) is a major component
of some traditional medicinal herbs present in honey, propolis and many plant
extracts.<o:p></o:p></span></span></div>
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<span lang="EN-US"><span style="font-family: "verdana" , sans-serif;">The study was aimed to illuminate the effect of
chrysin in the pathogenesis of ammonium chloride (NH4Cl) induced hyperammonemic
rat model in a dose dependent manner. Rats were injected with NH4Cl (100mg/kg
b.w.) by intraperitonially (i.p) thrice a week for 8 consecutive weeks for the
induction of experimental hyperammonemia. Hyperammonemic rats were treated with
chrysin by orally at a dose of 25, 50 & 100mg/kg b.w. respectively. </span></span></div>
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<span lang="EN-US"><span style="font-family: "verdana" , sans-serif;"><br /></span></span></div>
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<span lang="EN-US"><span style="font-family: "verdana" , sans-serif;">Protective effect of chrysin against hyperammonemia was evaluated by performing
biochemical estimations and morphopathological investigations of hematoxylin
and eosin stained sections of liver, brain and kidney tissues. Supplementation
of chrysin reinstated the levels of blood ammonia, plasma urea, uric acid,
total bilirubin, creatinine, brain glutamate, glutamine, nitric oxide (NO) and
the activities of Na+/K+-ATPase, and liver marker enzymes. </span></span></div>
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<span style="font-family: "verdana" , sans-serif;"><a href="https://upload.wikimedia.org/wikipedia/commons/thumb/e/e1/Chrysin_molecule_ball.png/220px-Chrysin_molecule_ball.png" imageanchor="1" style="clear: right; float: right; margin-bottom: 1em; margin-left: 1em;"><img border="0" src="https://upload.wikimedia.org/wikipedia/commons/thumb/e/e1/Chrysin_molecule_ball.png/220px-Chrysin_molecule_ball.png" /></a></span></div>
<span style="font-family: "verdana" , sans-serif;">On the other hand
increased level of plasma urea was observed in chrysin treated rats as compared
with hyperammonemic rats. Chrysin administration caused distortion of hepatic,
brain and kidney architecture as shown by histological examination.<o:p></o:p></span><br />
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<span lang="EN-US" style="font-size: 12pt;"><span style="font-family: "verdana" , sans-serif;"><span style="background-color: yellow;">Chrysin at a dose (100mg/kg b.w.) showed an
utmost decline in the level of all biochemical estimations</span>. Both biochemical
and morphological studies clearly revealed that <span style="background-color: yellow;">chrysin protects against cell
injury</span> induced by <a href="https://www.blogger.com/null" name="OLE_LINK6"></a><a href="https://www.blogger.com/null" name="OLE_LINK5">ammonia intoxication </a>in a
dose-response manner with respect to endogenous antioxidants and hypoammonemic
effects.</span></span><br />
<span lang="EN-US" style="font-size: 12pt;"><span style="font-family: "verdana" , sans-serif;"><br /></span></span>
<span lang="EN-US" style="font-family: "times new roman" , serif; font-size: 12.0pt;"><br /></span></div>
BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com0tag:blogger.com,1999:blog-6405325709567335968.post-68873088737695775512016-07-20T17:23:00.002+02:002016-07-20T17:23:53.010+02:00Chronic Rhinosinusitis Healed with Propolis<div dir="ltr" style="text-align: left;" trbidi="on">
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<i><b><span style="color: purple;">A really good study confirming the beneficial effects of propolis for chronic sinus ailments such as rhinosinusitis. Another interesting point is the consistent effect of its healing, </span></b></i><i><b><span style="color: purple;">protective </span></b></i><i><b><span style="color: purple;">properties on injuries, especially in mucous linings of the body.</span></b></i></div>
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<span style="font-family: "trebuchet ms" , sans-serif; font-size: x-large;"><b>Chronic Rhinosinusitis Healed with Propolis</b></span></div>
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<span style="font-family: "trebuchet ms" , sans-serif;"><span lang="EN-US"></span></span></div>
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<span lang="EN-US"><span style="font-family: "trebuchet ms" , sans-serif;"><span style="font-size: xx-small;"><a href="https://www.thieme-connect.com/products/ejournals/html/10.1055/s-0036-1579664" target="_blank">Int Arch Otorhinolaryngol. 2016 Jul</a>. </span><o:p></o:p></span></span></div>
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<span lang="EN-US"><span style="font-family: "trebuchet ms" , sans-serif;"><span style="font-size: xx-small;"><br /></span></span></span></div>
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<a href="https://3.bp.blogspot.com/-gbswDZkteq0/V46iV88ijQI/AAAAAAAAIfc/yKmpACGwmgQNFowDFPozyRZCmjRk_DDygCLcB/s1600/blog_int_arch_otorhino.jpg" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img border="0" src="https://3.bp.blogspot.com/-gbswDZkteq0/V46iV88ijQI/AAAAAAAAIfc/yKmpACGwmgQNFowDFPozyRZCmjRk_DDygCLcB/s1600/blog_int_arch_otorhino.jpg" /></a></div>
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<span lang="EN-US"><span style="font-family: "trebuchet ms" , sans-serif;"><u>INTRODUCTION</u>:<o:p></o:p></span></span></div>
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<span lang="EN-US"><span style="font-family: "trebuchet ms" , sans-serif;">Mechanical trauma to the nasal mucosa
increases the risk of synechia formation, especially after chronic
rhinosinusitis and nasal surgeries.<o:p></o:p></span></span></div>
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<span lang="EN-US"><span style="font-family: "trebuchet ms" , sans-serif;"><u>OBJECTIVE</u>:<o:p></o:p></span></span></div>
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<span lang="EN-US"><span style="font-family: "trebuchet ms" , sans-serif;">This study was carried to assess the effect
of propolis administration in healing injured nasal mucosa in rats.<o:p></o:p></span></span></div>
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<span lang="EN-US"><span style="font-family: "trebuchet ms" , sans-serif;"><u>METHODS</u>:<o:p></o:p></span></span></div>
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<span lang="EN-US"><span style="font-family: "trebuchet ms" , sans-serif;">We randomly divided eighteen rats into
three equal experimental groups: (1) non-treated group; (2) gum tragacanth
(suspending agent for propolis) treated group; and (3) propolis treated group.
The non-treated group received no treatment for 15 days. The second group
received gum tragacanth administration (5 ml/kg, orally) once daily for 15
days. The third group received propolis suspension orally at a dose of 100
mg/kg once daily for 15 days. At the beginning of this study, we induced
unilateral mechanical nasal trauma on the right nasal mucosa of all rats in the
three groups using a brushing technique. A pathologist stained tissue samples
using hematoxylin and examined eosin by using a light microscope.<o:p></o:p></span></span></div>
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<table cellpadding="0" cellspacing="0" class="tr-caption-container" style="float: right; margin-left: 1em; text-align: right;"><tbody>
<tr><td style="text-align: center;"><a href="https://1.bp.blogspot.com/-Zfs-1RtHVB4/V46wMrQXgwI/AAAAAAAAIfs/C4v9bfl-pkw08yRlCF-IEEEDKevUtgxRwCLcB/s1600/blog_mucosa_horiz.jpg" imageanchor="1" style="clear: right; margin-bottom: 1em; margin-left: auto; margin-right: auto;"><img border="0" height="88" src="https://1.bp.blogspot.com/-Zfs-1RtHVB4/V46wMrQXgwI/AAAAAAAAIfs/C4v9bfl-pkw08yRlCF-IEEEDKevUtgxRwCLcB/s400/blog_mucosa_horiz.jpg" width="400" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;"><span style="background-color: #f0f0f0; font-family: "verdana" , "arial" , "helvetica" , sans-serif; font-size: 11px; font-style: italic; line-height: 16.8px;">Photomicrographs of (1) non-treated, (2) gum (3) propolis</span></td></tr>
</tbody></table>
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<span lang="EN-US"><span style="font-family: "trebuchet ms" , sans-serif;"><u>RESULTS</u>:<o:p></o:p></span></span></div>
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<span lang="EN-US"><span style="font-family: "trebuchet ms" , sans-serif;">The severity of inflammation was milder
with the absence of ulcerations in the propolis treated group compared with the
non-treated and gum tragacanth groups. Goblet cell and ciliated cell loss was
substantially lower in patients treated with propolis compared with groups
without treatment and those treated with gum tragacanth.<o:p></o:p></span></span></div>
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<span lang="EN-US"><span style="font-family: "trebuchet ms" , sans-serif;"><u>CONCLUSION</u>:<o:p></o:p></span></span></div>
<span style="font-family: "trebuchet ms" , sans-serif;"><span style="background-color: yellow;">Propolis decreased inflammation and
enhanced healing of wounds of the nasal mucosa </span>in rats.</span><br />
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<span lang="EN-US"><span style="font-family: "trebuchet ms" , sans-serif;"><br /></span></span></div>
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<span lang="EN-US"> </span></div>
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BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com0tag:blogger.com,1999:blog-6405325709567335968.post-57556739721403655662016-06-13T16:13:00.000+02:002016-06-13T16:13:15.929+02:00Propolis Reduces Risk of Cataracts<div dir="ltr" style="text-align: left;" trbidi="on">
<b><i><span style="color: purple;">This eye-opening study provides evidence of another benefit from the super antioxidant power of propolis. This is important news for those suffering from diabetes, as sugar cataracts are common. Previous studies have also determined propolis to be a safe antidiabetic alternative for diabetics to consume propolis even at 50-200mg/kg/BW. </span></i></b><br />
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<span style="font-family: "verdana" , sans-serif;"><b>Propolis, a Constituent of Honey, Inhibits the Development
of Sugar Cataracts and High-Glucose-Induced Reactive Oxygen Species in Rat
Lenses</b><o:p></o:p></span></div>
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<a href="http://www.hindawi.com/journals/joph/2016/1917093/abs/" style="font-family: verdana, sans-serif; font-size: x-small;" target="_blank">J Ophthalmol</a><span style="font-family: "verdana" , sans-serif; font-size: xx-small;">. 2016, April 19;2016:1917093</span></div>
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<span style="font-family: "verdana" , sans-serif; font-size: xx-small;"><br /></span></div>
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<div class="separator" style="clear: both; text-align: center;">
<a href="https://4.bp.blogspot.com/-4vAU1nkAwmI/V1627IsycXI/AAAAAAAAIeo/l0_0u091vlkRAH6qNjmwC4DpyYd63r8sgCKgB/s1600/blog_j_ophthalmology.png" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img border="0" src="https://4.bp.blogspot.com/-4vAU1nkAwmI/V1627IsycXI/AAAAAAAAIeo/l0_0u091vlkRAH6qNjmwC4DpyYd63r8sgCKgB/s1600/blog_j_ophthalmology.png" /></a></div>
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<span style="font-family: "verdana" , sans-serif;"><u>Purpose</u> </span></div>
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<span style="font-family: "verdana" , sans-serif;">This study investigated the effects of oral
propolis on the progression of <a href="https://en.wikipedia.org/wiki/Galactose" target="_blank">galactose</a>-induced sugar cataracts in rats and
the in vitro effects of propolis on high-glucose-induced reactive oxygen
species (ROS) and cell death in cultured rat lens cells (RLECs).<o:p></o:p></span></div>
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<span style="font-family: "verdana" , sans-serif;"><br /></span></div>
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<span style="font-family: "verdana" , sans-serif;"><u>Methods</u> </span></div>
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<span style="font-family: "verdana" , sans-serif;">Galactose-fed rats and RLECs cultured in high
glucose (55 mM) medium were treated with propolis or vehicle control. Relative
lens opacity was assessed by densitometry and changes in lens morphology by
histochemical analysis. Intracellular ROS levels and cell viability were
measured.<o:p></o:p></span></div>
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<span style="font-family: "verdana" , sans-serif;"><br /></span></div>
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<span style="font-family: "verdana" , sans-serif;"><u>Results</u> </span></div>
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<span style="font-family: "verdana" , sans-serif;">Oral administration of propolis significantly
inhibited the onset and progression of cataract in 15% and 25% of galactose-fed
rats, respectively. RLECs cultured with high glucose showed a significant
increase in ROS expression with reduced cell viability. Treatment of these
RLECs with 5 and 50 μg/mL propolis cultured significantly reduced ROS levels
and increased cell viability, indicating that the antioxidant activity of
propolis protected cells against ROS-induced damage.<o:p></o:p></span><br />
<table cellpadding="0" cellspacing="0" class="tr-caption-container" style="float: right; margin-left: 1em; text-align: right;"><tbody>
<tr><td style="text-align: center;"><a href="https://2.bp.blogspot.com/-NutlOuBsUTI/V166-KmmCkI/AAAAAAAAIes/g4kZ2lUmOiMP-3l3RlVl9aLORz8NZ5lqACLcB/s1600/blog_j_ophthalmology_graph.png" imageanchor="1" style="clear: right; margin-bottom: 1em; margin-left: auto; margin-right: auto;"><img border="0" height="227" src="https://2.bp.blogspot.com/-NutlOuBsUTI/V166-KmmCkI/AAAAAAAAIes/g4kZ2lUmOiMP-3l3RlVl9aLORz8NZ5lqACLcB/s320/blog_j_ophthalmology_graph.png" width="320" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;">figure 2</td></tr>
</tbody></table>
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<span style="font-family: "verdana" , sans-serif; font-size: 12.0pt;"><u>Conclusion</u> </span><br />
<span style="font-family: "verdana" , sans-serif; font-size: 12.0pt;"><span style="background-color: yellow;">Propolis significantly inhibited the onset
and progression of sugar cataract in rats and mitigated high-glucose-induced
ROS production and cell death</span>. These effects may be associated with the ability
of propolis to inhibit hyperglycemia-evoked oxidative or osmotic stress-induced
cellular insults.</span><br />
<span style="font-family: "verdana" , sans-serif; font-size: 12.0pt;"><br /></span>
<span style="font-family: "times new roman" , serif; font-size: 12.0pt;"><br /></span>
<span style="font-family: "times new roman" , serif; font-size: 12.0pt;"><br /></span></div>
BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com0tag:blogger.com,1999:blog-6405325709567335968.post-7283428783832672752016-05-22T09:21:00.001+02:002018-03-15T15:42:02.372+01:00Allergy Relief Effective with Propolis<div dir="ltr" style="text-align: left;" trbidi="on">
<b><i><span style="color: purple;">This study reaffirms once again, the holistic effects of propolis on mucous linings of the body, in particular the nasal passageway. Its anti-inflammatory properties also provide anti-allergic effects, ideal for those who suffer from respiratory ailments. Just another amazing product made by honeybees.</span></i></b><br />
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<span style="font-family: "verdana" , sans-serif;"><b>Effects of propolis in an experimental rat model of allergic
rhinitis</b><o:p></o:p></span></div>
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<span style="font-family: "verdana" , sans-serif; font-size: xx-small;"><a href="http://www.amjoto.com/article/S0196-0709(16)30002-3/abstract" target="_blank">Am. J. Otoloranology, 2016 Apr 2</a></span></div>
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<a href="https://4.bp.blogspot.com/-qnByjFFxl1c/V0CWhuYgjKI/AAAAAAAAIeA/dlR7FhNGJakUzyVaf7WUTHlbvO8Pgkb-wCLcB/s1600/blog_j_otolorynology.jpg" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img border="0" src="https://4.bp.blogspot.com/-qnByjFFxl1c/V0CWhuYgjKI/AAAAAAAAIeA/dlR7FhNGJakUzyVaf7WUTHlbvO8Pgkb-wCLcB/s1600/blog_j_otolorynology.jpg" /></a></div>
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<span style="font-family: "verdana" , sans-serif;"><i><b><br /></b></i></span></div>
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<span style="font-family: "verdana" , sans-serif;"><i><b><br /></b></i></span></div>
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<span style="font-family: "verdana" , sans-serif;"><i><b><br /></b></i></span></div>
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<span style="font-family: "verdana" , sans-serif;"><i><b><br /></b></i></span></div>
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<span style="font-family: "verdana" , sans-serif;"><i><b><br /></b></i></span></div>
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<u style="font-family: Verdana, sans-serif;">Purpose</u></div>
<div class="MsoNormal">
<span style="font-family: "verdana" , sans-serif;">The aim of this study was to determine the anti-allergic
activity of propolis in an ovalbumin-induced rat model of allergic <a href="https://en.wikipedia.org/wiki/Rhinitis" target="_blank">rhinitis</a>.<o:p></o:p></span></div>
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<span style="font-family: "verdana" , sans-serif;"><u>Materials and methods</u><o:p></o:p></span></div>
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<span style="font-family: "verdana" , sans-serif;">This prospective experimental study was conducted at Hakan
Çetinsaya Clinical and Experimental Animal Research Center with 30 rats. After
sensitization of all rats with 0.3 mg intraperitoneal ovalbumin plus 30 mg
aluminum hydroxide for 14 days (first phase), rats were divided to five groups.
In the second phase of the study 10 μL of ovalbumin was applied to each nostril
for 21 days. Together with second phase, ketotifen (n:6), oral propolis (n:6),
intranasal propolis (n:6) and intranasal mometasone furoate (n:6) were given to
rats. A control group (n:4)(salin) and sham group (n:2) were planned. Symptoms
were assessed on days 19, 22, 25, 30 and 35, resulting in 5 symptom scores:
symptom scores 1–5. On day 35, nasal tissue was removed and histological
examination was performed.<o:p></o:p></span></div>
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<span style="font-family: "verdana" , sans-serif;"><u>Results</u><o:p></o:p></span></div>
<div class="MsoNormal">
<span style="font-family: "verdana" , sans-serif;">When <span style="background-color: yellow;">rats that received systemic and intranasal propolis</span>
were compared to controls, ciliary loss, inflammation, increase in goblet
cells, vascular proliferation, eosinophil count, chondrocytes and allergic
rhinitis symptom score were found to be decreased (p < 0.05).<o:p></o:p></span></div>
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<span style="font-family: "verdana" , sans-serif;"><u>Conclusions</u><o:p></o:p></span></div>
<span style="font-family: verdana, sans-serif;">It was found that </span><span style="background-color: yellow; font-family: verdana, sans-serif;">propolis had anti-allergic effects on
allergic symptom scores and nasal histology</span><span style="font-family: verdana, sans-serif;">.</span><br />
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<o:p></o:p></div>
</div>
BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com0tag:blogger.com,1999:blog-6405325709567335968.post-47077279610532596222016-03-29T00:09:00.000+02:002016-05-24T11:57:51.708+02:00Lungs Protected from Pulmonary Fibrosis with Propolis<div dir="ltr" style="text-align: left;" trbidi="on">
<i><b><span style="color: purple;">Frequently found as an aid for pulmonary conditions and respiratory ailments, this study found propolis was better at protecting lungs from the deliberate scarring of bleomycin versus prednisolone and its known negative side effects.</span></b></i><br />
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<span style="font-family: "verdana" , sans-serif;"><b>Ultrastructural investigation of the protective effects of
propolis on bleomycin induced pulmonary fibrosis</b><o:p></o:p></span></div>
<div class="MsoNormal">
<span style="font-family: "verdana" , sans-serif;"><a href="http://www.tandfonline.com/doi/abs/10.3109/10520295.2015.1123294?journalCode=ibih20" style="font-size: x-small;" target="_blank">Biotech Histochem</a><span style="font-size: xx-small;">. 2016 Mar 9:1-9</span></span></div>
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<span style="font-family: "verdana" , sans-serif;"><o:p></o:p></span></div>
<div class="separator" style="clear: both; text-align: center;">
<a href="https://1.bp.blogspot.com/-a8cdp8ynwwY/VvmnsIE-FDI/AAAAAAAAIc4/XTaxwsnVK8odchasjQBoevDiTBuTBBolg/s1600/blog_biotechnic_histochemistry.jpg" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img border="0" src="https://1.bp.blogspot.com/-a8cdp8ynwwY/VvmnsIE-FDI/AAAAAAAAIc4/XTaxwsnVK8odchasjQBoevDiTBuTBBolg/s1600/blog_biotechnic_histochemistry.jpg" /></a></div>
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<br /></div>
<div class="MsoNormal">
<span style="font-family: "verdana" , sans-serif;">We investigated the antioxidant and anti-inflammatory
effects of propolis on bleomycin induced lung fibrosis and compared these
effects to <a href="https://en.wikipedia.org/wiki/Prednisolone" target="_blank">prednisolone</a> treatment.<o:p></o:p></span></div>
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<br /></div>
<div class="MsoNormal">
<span style="font-family: "verdana" , sans-serif;">Forty rats were divided into four groups of ten: group 1 was
treated with intratracheal infusion of 0.2 ml physiological saline followed by
daily treatment with 0.5 ml physiological saline for 20 days. In the remaining
groups (groups 2 - 4), 5 mg/kg bleomycin was given via the trachea. Rats in
group 2 were given 0.5 ml physiological saline. <span style="background-color: yellow;">Rats in group 3 were treated
with 100 mg/kg propolis</span>, and 10 mg/kg prednisolone was given to rats in group
4.<o:p></o:p></span></div>
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<br /></div>
<div class="MsoNormal">
<span style="font-family: "verdana" , sans-serif;">The treatments for all groups were continued for 20 days. On
postoperative day<table align="center" cellpadding="0" cellspacing="0" class="tr-caption-container" style="float: right; margin-left: 1em; text-align: right;"><tbody>
<tr><td style="text-align: center;"><a href="https://1.bp.blogspot.com/-fNF7ga4RY6c/Vvmpc5ln6ZI/AAAAAAAAIdE/fM8XLrcZTzwx-MB7dEO7vjn3e4qmGEN1A/s1600/Journal.pmed.0020314.g001_Osteopontin.png" imageanchor="1" style="margin-left: auto; margin-right: auto;"><img alt="Histopathology of idiopathic pulmonary fibrosis" border="0" height="200" src="https://1.bp.blogspot.com/-fNF7ga4RY6c/Vvmpc5ln6ZI/AAAAAAAAIdE/fM8XLrcZTzwx-MB7dEO7vjn3e4qmGEN1A/s200/Journal.pmed.0020314.g001_Osteopontin.png" title="photo courtesy of PLoS Medicine" width="168" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;">PLoS Medicine</td></tr>
</tbody></table>
21, blood and lung samples were taken for biochemistry,
histopathology and electron microscopy evaluation. We compared oxidative stress
parameters and found lower malondialdehyde and myeloperoxidase levels, and
higher total sulfhydryl levels and catalase activities for the bleomycin +
propolis group than for the bleomycin and bleomycin + prednisolone groups. The
highest mean fibrosis score was detected in the bleomycin group.<o:p></o:p></span></div>
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<br />
<div class="MsoNormal">
<span style="font-family: "verdana" , sans-serif;">Although the mean fibrosis scores of the bleomycin +
propolis and bleomycin + prednisolone groups were not significantly different,
<span style="background-color: yellow;">electron microscopy revealed that propolis diminished bleomycin induced lung
fibrosis more effectively than prednisolone</span>. The effects of propolis might be
due to<span style="background-color: yellow;"> its potent antioxidant and anti-inflammatory properties.</span><o:p></o:p></span></div>
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BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com0tag:blogger.com,1999:blog-6405325709567335968.post-18004465029301731782016-02-06T18:44:00.002+01:002016-06-09T18:59:27.051+02:00Propolis Effective in Humans for Antifungal Activity<div dir="ltr" style="text-align: left;" trbidi="on">
<b><i><span style="color: purple;">This study is very exciting proving what's been known for many years - propolis is antifungal. Now, </span></i></b><b><i><span style="color: purple;">this in-vitro study confirms that patients infected with fungi had a significant reduction, which is very exciting news for those suffering from Lyme Disease and others with allergies associated with mold.</span></i></b><br />
<br />
<b><span style="color: #333333; font-family: "verdana" , sans-serif;">Antifungal Activity of Propolis Against Yeasts Isolated From Blood
Culture: In Vitro Evaluation</span></b><br />
<div class="MsoNormal" style="background: white; line-height: 15.6pt;">
<span style="color: #333333; font-family: "verdana" , sans-serif;"><span style="font-size: xx-small;"><a href="http://onlinelibrary.wiley.com/doi/10.1002/jcla.21889/abstract" target="_blank">J ClinLab Anal</a>. 2016 Jan 20</span><span style="font-size: 10pt;"><o:p></o:p></span></span></div>
<div class="separator" style="clear: both; text-align: center;">
<a href="https://2.bp.blogspot.com/-KoXYdq65_94/VrYpPUtjyVI/AAAAAAAAIbs/I8icVsocuKE/s1600/blog_j_clin_lab_analysis.jpg" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img border="0" src="https://2.bp.blogspot.com/-KoXYdq65_94/VrYpPUtjyVI/AAAAAAAAIbs/I8icVsocuKE/s1600/blog_j_clin_lab_analysis.jpg" /></a></div>
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<div class="MsoNormal">
<span style="font-family: Verdana, sans-serif;"><u><b>BACKGROUND</b></u>: </span></div>
<div class="MsoNormal">
<span style="font-family: Verdana, sans-serif;">Due to the failure of available antifungal agents in the
treatment of candidemia and the toxic activities of these drugs, a lot of
researches are being conducted to develop new nontoxic and effective antifungal
agents for optimal control of fungal pathogens. The aim of this study is to
evaluate the in vitro antifungal activity of propolis against yeasts isolated
from the blood cultures of intensive care unit patients.<o:p></o:p></span></div>
<div class="MsoNormal">
<span style="font-family: Verdana, sans-serif;"><br /></span></div>
<div class="MsoNormal">
<span style="font-family: Verdana, sans-serif;"><u><b>METHODS</b></u>: </span></div>
<div class="MsoNormal">
<span style="font-family: Verdana, sans-serif;">Seventy-six strains were included in this study. The in
vitro antifungal activity of propolis, fluconazole (FLU), and itraconazole
(ITR) was investigated by the microdilution broth methods (CLSI guidelines
M27-A3 for yeast). The propolis sample was collected from Kayseri, Turkey.<o:p></o:p></span></div>
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<span style="font-family: Verdana, sans-serif;"><br /></span></div>
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<span style="font-family: Verdana, sans-serif;"><u><b>RESULTS</b></u>: </span></div>
<div class="MsoNormal">
<span style="font-family: Verdana, sans-serif;">Of the 76 isolates, 33 were identified as Candida albicans
while 37 were C. parapsilosis, three were C. tropicalis, and three were
identified as C. glabrata. The geometric mean range for MIC (μg/ml) with regard
to all isolates was 0.077 to 3 μg/ml for FLU and ITR, and 0.375 to 0.70 μg/ml
for propolis. It was shown that <span style="background-color: yellow;">propolis had significant antifungal activity
against all Candida strains</span> and the MIC range of propolis was determined as
0185 to 3 μg/ml.</span></div>
<table cellpadding="0" cellspacing="0" class="tr-caption-container" style="float: right; margin-left: 1em; text-align: right;"><tbody>
<tr><td style="text-align: center;"><a href="https://upload.wikimedia.org/wikipedia/commons/thumb/e/e6/Candida_albicans_2.jpg/800px-Candida_albicans_2.jpg" imageanchor="1" style="clear: right; margin-bottom: 1em; margin-left: auto; margin-right: auto;"><span style="font-family: Verdana, sans-serif;"><img border="0" height="200" src="https://upload.wikimedia.org/wikipedia/commons/thumb/e/e6/Candida_albicans_2.jpg/800px-Candida_albicans_2.jpg" width="320" /></span></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;"><span style="font-family: Verdana, sans-serif;">By GrahamColm - Own work, CC BY-SA 3.0, </span><br />
<span style="font-family: Verdana, sans-serif;">https://commons.wikimedia.org/w/index.php?curid=10921762</span></td></tr>
</tbody></table>
<span style="font-family: Verdana, sans-serif;"><o:p></o:p><br /></span>
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<span style="font-family: Verdana, sans-serif;"><br /></span></div>
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<span style="font-family: Verdana, sans-serif;"><u><b>CONCLUSION</b></u>:</span></div>
<div class="MsoNormal">
<span style="font-family: Verdana, sans-serif;">This study demonstrated that <span style="background-color: yellow;">propolis had significant
antifungal activity against yeasts isolated from blood culture </span>compared with
FLU and ITR. The propolis MIC in azole-resistant strains such as C. glabrata
was found lower than the FLU MIC.</span></div>
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<o:p></o:p></div>
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BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com0tag:blogger.com,1999:blog-6405325709567335968.post-18088327986800514662016-01-23T19:20:00.001+01:002016-01-23T19:20:59.859+01:00Live Longer Eating Bee Products and Keeping Bees<div dir="ltr" style="text-align: left;" trbidi="on">
<b><i><span style="color: purple;">This amazing study confirms that keeping bees and consuming bee products can prolong life! DNA results show chromosomes lengthen rather than shorten over time for beekeepers and for those who consume bee products. So, if you haven't eaten honey, bee pollen, propolis or royal jelly today, then it's time to start. Live longer with Apitherapy! </span></i></b><div>
<span style="color: purple;"><b><i><br /></i></b></span><div>
<div class="MsoNormal">
<span lang="EN"><span style="font-family: Verdana, sans-serif;"><b>The relationship
between telomere length and beekeeping among Malaysians</b><o:p></o:p></span></span></div>
<div class="MsoNormal">
<span style="font-family: Verdana, sans-serif; font-size: xx-small;"><a href="http://link.springer.com/article/10.1007%2Fs11357-015-9797-6">AGE</a>, June 2015, 37:58</span></div>
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<span style="font-family: Verdana, sans-serif; font-size: xx-small;"><br /></span></div>
<div class="MsoNormal">
<span style="font-family: Verdana, sans-serif;"><o:p></o:p></span></div>
<div class="separator" style="clear: both; text-align: center;">
<a href="http://2.bp.blogspot.com/-u-McFozex48/VqO7sL2jcnI/AAAAAAAAIaw/umFh8yBNHSY/s1600/blog_j_age.jpg" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img border="0" src="http://2.bp.blogspot.com/-u-McFozex48/VqO7sL2jcnI/AAAAAAAAIaw/umFh8yBNHSY/s1600/blog_j_age.jpg" /></a></div>
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<span style="font-family: Verdana, sans-serif;"><b>Abstract</b><o:p></o:p></span></div>
<div class="MsoNormal">
<span style="font-family: Verdana, sans-serif;">The belief that beekeepers live longer than anyone else is
present since ages. However, no research has been done to explore the longevity
of life in beekeepers. Here, we investigated the telomere length in 30 male
beekeepers and 30 male non-beekeepers and associated them with the longevity of
life using Southern analysis of terminal restriction fragments (TRFs) generated
by Hinf I/Rsa I digestion of human genomic DNA using TeloTAGGG Telomere Length
Assay. </span></div>
<div class="separator" style="clear: both; text-align: center;">
<a href="https://upload.wikimedia.org/wikipedia/commons/6/6a/Telomere.png" imageanchor="1" style="clear: right; float: right; margin-bottom: 1em; margin-left: 1em;"><span style="font-family: Verdana, sans-serif;"></span></a></div>
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<div class="separator" style="clear: both; text-align: center;">
<a href="https://upload.wikimedia.org/wikipedia/commons/6/6a/Telomere.png" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img border="0" height="120" src="https://upload.wikimedia.org/wikipedia/commons/6/6a/Telomere.png" width="200" /></a></div>
<div class="MsoNormal">
<span style="font-family: Verdana, sans-serif;">Interestingly, we found that the <span style="background-color: yellow;">telomere length of male beekeepers was
significantly longer than those of male non-beekeepers</span> with a p value of less
than 0.05, suggesting that beekeepers may have longer life compared to
non-beekeepers. We further found that the <span style="background-color: yellow;">consumption of bee products for a
long period and frequent consumption of bee products per day are associated
with telomere length</span>. An increase of year in consuming bee products is associated with a mean increase in </span><span style="font-family: Verdana, sans-serif;">telomere length of 0.258 kbp. In addition, an increase
in frequency of eating bee products per day was also associated with a mean
increase of 2.66 kbp in telomere length.</span></div>
<div class="separator" style="clear: both; text-align: center;">
<a href="http://3.bp.blogspot.com/-jwu-T1ZBJSs/VqO_pqzjOII/AAAAAAAAIbM/STMLtWkjj8U/s1600/beekeeper_naturel_BHFlogo.jpg" imageanchor="1" style="clear: right; float: right; margin-bottom: 1em; margin-left: 1em;"><img border="0" height="200" src="http://3.bp.blogspot.com/-jwu-T1ZBJSs/VqO_pqzjOII/AAAAAAAAIbM/STMLtWkjj8U/s200/beekeeper_naturel_BHFlogo.jpg" width="200" /></a></div>
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<span style="font-family: Verdana, sans-serif;"><br /></span></div>
<div class="MsoNormal">
<span style="font-family: Verdana, sans-serif;">These results suggested that <span style="background-color: yellow;">bee
products might play some roles in telomere length maintenance</span>.<o:p></o:p></span></div>
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<span style="font-family: Verdana, sans-serif;"><br /></span></div>
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BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com0tag:blogger.com,1999:blog-6405325709567335968.post-7343038402082388772015-12-29T23:20:00.001+01:002015-12-29T23:36:12.534+01:00Diabetic Wounds Heal Better with Propolis<div dir="ltr" style="text-align: left;" trbidi="on">
<span style="color: purple; font-family: Times, Times New Roman, serif;"><i><b>Enhancing the healing process is a natural aspect of propolis which protects the body as it does the beehive. This has been verified in other <a href="http://beehealthyfarms.blogspot.fr/#uds-search-results" target="_blank">studies</a>, yet this study focused on more delicate wound healing conditions, such as those of diabetic mice. Thank goodness for the additional antimicrobial properties of propolis to speed </b></i></span><i style="color: purple; font-family: Times, 'Times New Roman', serif;"><b>along the </b></i><i style="color: purple; font-family: Times, 'Times New Roman', serif;"><b>healing process. Fortunately, there are preparations of propolis </b></i><i style="color: purple; font-family: Times, 'Times New Roman', serif;"><b>available on the market </b></i><i style="color: purple; font-family: Times, 'Times New Roman', serif;"><b>that address wound healing.</b></i><br />
<br />
<div class="MsoNormal">
<span style="font-family: Verdana, sans-serif;"><b>Topical Application of Propolis Enhances Cutaneous Wound
Healing by Promoting TGF-Beta/Smad-Mediated Collagen Production in a
Streptozotocin-Induced Type I Diabetic Mouse Model</b><o:p></o:p></span></div>
<div class="MsoNormal">
<span style="font-family: Verdana, sans-serif;"><span style="font-size: xx-small;"><a href="http://www.karger.com/Article/FullText/430221" target="_blank">Cell Physiol Biochem. 2015 Sep 18;37(3):940-954</a></span></span></div>
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<a href="https://www.karger.com/WebMaterial/ShowProduktePic/224332?imgType=1&file=cover.jpg" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img border="0" height="200" src="https://www.karger.com/WebMaterial/ShowProduktePic/224332?imgType=1&file=cover.jpg" width="150" /></a></div>
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<span style="font-family: Verdana, sans-serif;"><u>BACKGROUND/AIMS</u>:<o:p></o:p></span></div>
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<span style="font-family: Verdana, sans-serif;">Impaired wound healing is considered to be one of the most
serious complications associated with diabetes as it significantly increases
the susceptibility of patients to infection. Propolis is a natural bee product
used extensively in foods and beverages that has significant benefits to human
health. In particular, <span style="background-color: yellow;">propolis has antioxidant, anti-inflammatory and
analgesic effects that could be useful for improving wound healing</span>. In this
study, we investigated the effects of topical application of propolis on the
healing and closure of diabetic wounds in a streptozotocin (STZ)-induced type I
diabetic mouse model.</span></div>
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<span style="font-family: Verdana, sans-serif;"><u>METHODS</u>:<o:p></o:p></span></div>
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<span style="font-family: Verdana, sans-serif;">Sixty male mice were distributed equally into 3 experimental
groups: group 1, non-diabetic control mice; group 2, diabetic mice; and group
3, diabetic mice treated daily with a topical application of propolis.</span><br />
<div class="separator" style="clear: both; text-align: center;">
<span style="font-family: Verdana, sans-serif;"><a href="http://3.bp.blogspot.com/-cw_ADnG-RCs/VoMEs9f_jKI/AAAAAAAAIaE/25HnZ1XDKuo/s1600/propolis_bee_hive_BHF1280.JPG" imageanchor="1" style="clear: right; float: right; margin-bottom: 1em; margin-left: 1em;"><img border="0" height="133" src="http://3.bp.blogspot.com/-cw_ADnG-RCs/VoMEs9f_jKI/AAAAAAAAIaE/25HnZ1XDKuo/s200/propolis_bee_hive_BHF1280.JPG" width="200" /></a></span></div>
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<span style="font-family: Verdana, sans-serif;"><u>RESULTS</u>:<o:p></o:p></span></div>
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<span style="font-family: Verdana, sans-serif;">We found that diabetic mice exhibited delayed wound closure
characterized by a significant decrease in the levels of TGF-β1 and a prolonged
elevation of the levels of inflammatory cytokines (IL-1β, IL-6 and TNF-α) and
MMP9 in wound tissues compared with control non-diabetic mice. Moreover, the
wound tissues of diabetic mice showed a marked reduction in the phosphorylation
of Smad2 and Smad3 as well as a marked reduction in collagen production.
Interestingly, compared with untreated diabetic mice, <span style="background-color: yellow;">topical application of
propolis significantly enhanced the closure of diabetic wounds</span> and decreased
the levels of IL-1β, IL-6, TNF-α and MMP9 to near normal levels. Most
importantly, compared with untreated diabetic mice, the treatment of diabetic
mice with propolis significantly enhanced the production of collagen via the
TGF-β1/Smad2,3 signaling axis in wounded tissues.</span></div>
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<span style="font-family: Verdana, sans-serif;"><u>CONCLUSION</u>:<o:p></o:p></span></div>
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<span style="font-family: Verdana, sans-serif;">Our findings reveal the molecular mechanisms underlying the
improved healing and closure of diabetic wounds following topical propolis
application.</span></div>
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BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com1tag:blogger.com,1999:blog-6405325709567335968.post-24622261216629527702015-10-31T12:07:00.002+01:002015-10-31T12:07:27.445+01:00Intestinal Linings Protected by Propolis from Radiation<div dir="ltr" style="text-align: left;" trbidi="on">
<b><i><span style="color: purple;">New findings from this study reaffirms the protective effects of propolis from radiation exposure. This is quite impressive, as propolis is </span></i></b><b><i><span style="color: purple;">documented to </span></i></b><b><i><span style="color: purple;">work well on mucous linings of the body and protecting organs such as the liver, kidneys and spleen. This study builds upon the rich database of research which continues to reveal this substance as an essential adjuvant for patients undergoing radiation therapy. Furthermore, the anti-cancerous effects that propolis also provides should make </span></i></b><b><i><span style="color: purple;">physicians eager to incorporate propolis in their protocols</span></i></b><b><i><span style="color: purple;">. </span></i></b><br />
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<span style="font-family: Verdana, sans-serif;"><b>Propolis aqueous extract preserves functional integrity of
murine intestinal mucosa after exposure to ionizing radiation</b><o:p></o:p></span></div>
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<span style="font-size: xx-small;"><span style="font-family: Verdana, sans-serif;"><a href="http://www.sciencedirect.com/science/article/pii/S1382668915300855" target="_blank">Environ Toxicol Pharmacol</a>. 2015 Oct 9;40(3):901-906</span></span></div>
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<span style="font-family: Verdana, sans-serif;"><o:p></o:p></span></div>
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<a href="http://3.bp.blogspot.com/-VJ72eqBfcTQ/VjSbg_zmPPI/AAAAAAAAITw/ASFEvN10-yA/s1600/blog_environ_toxic_pharmacology.jpg" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img border="0" src="http://3.bp.blogspot.com/-VJ72eqBfcTQ/VjSbg_zmPPI/AAAAAAAAITw/ASFEvN10-yA/s1600/blog_environ_toxic_pharmacology.jpg" /></a></div>
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<span style="font-family: Verdana, sans-serif;"><u>Highlights</u>: </span></div>
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<span style="font-family: Verdana, sans-serif; font-size: x-small;">- Histological and biochemical evidence of intestinal damage
seen after irradiation</span></div>
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<span style="font-family: Verdana, sans-serif; font-size: x-small;">- Parameters for intestinal function measured in tissue
homogenates and plasma</span></div>
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<span style="font-family: Verdana, sans-serif; font-size: x-small;">- Propolis extract prevents histological and
biochemical radiation-induced changes</span></div>
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<span style="font-family: Verdana, sans-serif; font-size: x-small;">- Beneficial effect of propolis water extract due
mainly to caffeic acid derivatives</span></div>
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<o:p></o:p></div>
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<o:p></o:p></div>
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<span style="font-family: Verdana, sans-serif;"><br /></span></div>
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<span style="font-family: Verdana, sans-serif;">The ability of a specially prepared water propolis extract
(PWE) to preserve the functional activity of the intestinal mucosa after
radiation exposure was studied. PWE was given orally (650mg/kg) to rats five
days prior to irradiation by 6Gy and continued for further two days. Rats were
sacrificed 24h later, intestinal segments were examined histologically and
homogenates were used to assess relevant biochemical parameters reflecting
intestinal injury. Irradiation led to a rise in the histological damage score,
a rise in tissue TNF-α and TBARS, and a decrease in sucrase, alkaline
phosphatase, GSH and cholecystokinin as well as a decrease in plasma
citrulline.<o:p></o:p></span></div>
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<span style="font-family: Verdana, sans-serif;"><br /></span></div>
<div class="separator" style="clear: both; text-align: center;">
<a href="http://4.bp.blogspot.com/-D_zFmy0Dj2w/VjSbyYZ1KfI/AAAAAAAAIT4/HJS34pVjZzU/s1600/blog_propolis_intestinal_radiation.jpg" imageanchor="1" style="clear: right; float: right; margin-bottom: 1em; margin-left: 1em;"><img border="0" height="212" src="http://4.bp.blogspot.com/-D_zFmy0Dj2w/VjSbyYZ1KfI/AAAAAAAAIT4/HJS34pVjZzU/s400/blog_propolis_intestinal_radiation.jpg" width="400" /></a></div>
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<span style="font-family: Verdana, sans-serif;">The findings reflect a decrease in intestinal functional
activity. <span style="background-color: yellow;">PWE preserved the intestinal integrity</span> and largely protected against
the changes induced in the histology damage score and all parameters measured,
<span style="background-color: yellow;">possibly as a result of the antioxidant and anti-inflammatory action of its
caffeic acid content</span>.</span></div>
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BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com1tag:blogger.com,1999:blog-6405325709567335968.post-11743232517619394142015-09-11T20:54:00.001+02:002015-09-12T17:30:18.233+02:00Dental Plaque Reduced with Propolis Toothpaste<div dir="ltr" style="text-align: left;" trbidi="on">
<b><i><span style="color: purple;">Competing with propolis in the field of dentistry is tough. Propolis responds very well when in contact with mucous linings of the body. This super antioxidant also delivers antimicrobial, antifungal and antiseptic properties which make it very adaptable to numerous conditions found out of balance. A secret in finding good toothpaste is to look for the "propolis. If it's not brown, then it's not significant.</span></i></b><br />
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<span style="font-family: Verdana, sans-serif;"><b>The antiplaque efficacy of propolis-based herbal toothpaste:
A crossover clinical study</b><o:p></o:p></span></div>
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<a href="http://www.jnsbm.org/article.asp?issn=0976-9668;year=2015;volume=6;issue=2;spage=364;epage=368;aulast=Bhat;type=0" style="font-family: Verdana, sans-serif; font-size: x-small;" target="_blank">J Nat Sci Biol Med</a><span style="font-family: Verdana, sans-serif; font-size: xx-small;">. 2015 Jul-Dec;6(2):364-8</span></div>
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<a href="http://3.bp.blogspot.com/-FhjaYUhZrwU/VfMht6C2kuI/AAAAAAAAIOc/Ywtsu9mx0jM/s1600/blog_j_nat_scie_bio_med.jpg" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img border="0" height="200" src="http://3.bp.blogspot.com/-FhjaYUhZrwU/VfMht6C2kuI/AAAAAAAAIOc/Ywtsu9mx0jM/s200/blog_j_nat_scie_bio_med.jpg" width="152" /></a></div>
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<span style="font-family: Verdana, sans-serif;"><u>BACKGROUND</u>:</span></div>
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<span style="font-family: Verdana, sans-serif;">In recent years, herbal products have been suggested as an
economic, safe and probably effective alternative for prevention and control of
various oral diseases. But still there are some products which need to be
evaluated. Of lately, Propolis is one such product. To assess and compare the
efficacy of herbal dentifrice containing Propolis with <a href="https://en.wikipedia.org/wiki/Miswak" target="_blank">Miswak</a> and Colgate total
toothpastes in controlling plaque formation.<o:p></o:p></span></div>
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<span style="font-family: Verdana, sans-serif;"><u>MATERIALS AND METHODS</u>:</span><span style="font-family: Verdana, sans-serif;"> </span></div>
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<table cellpadding="0" cellspacing="0" class="tr-caption-container" style="float: right; text-align: right;"><tbody>
<tr><td style="text-align: center;"><a href="https://1.bp.blogspot.com/-XWDcq2hXbuE/VfMpeVUSWkI/AAAAAAAAIR8/9u5yAZfg_IA/s1600/dentifrice2_400.JPG" imageanchor="1" style="clear: right; margin-bottom: 1em; margin-left: auto; margin-right: auto;"><img alt="http://www.beehealthyfarms.com/product.php?id_product=85" border="0" height="200" src="http://1.bp.blogspot.com/-XWDcq2hXbuE/VfMpeVUSWkI/AAAAAAAAIR8/9u5yAZfg_IA/s200/dentifrice2_400.JPG" title="Propolia propolis toothpaste" width="200" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;">Propolia propolis herbal toothpaste</td></tr>
</tbody></table>
<span style="font-family: Verdana, sans-serif;">A double blind, randomized, crossover study design was
conducted among thirty healthy dental students. After oral prophylaxis all
subjects were given a washout product for one week period. Subjects were then
made to brush with (washout product) for 1 minute followed by 1 minute brushing
with assigned test product. The baseline MGMPI plaque scores were recorded.
Subjects were then refrained from oral hygiene for 24 hours, and were recalled
to be re-disclosed and re-measured for plaque formation. This procedure was
repeated according to crossover design after a washout period of (2 week).
Statistical tests used were Krukalwallis and Wilcoxon sign rank test.</span><br />
<span style="font-family: Verdana, sans-serif;"><br /></span>
<span style="font-family: Verdana, sans-serif;"><br /></span>
<span style="font-family: Verdana, sans-serif;"><u>RESULTS</u>:</span><br />
<span style="font-family: Verdana, sans-serif;">There was a significant difference in 24 hour score between
the test products evaluated. When the change from baseline to 24 hours was
analyzed, the test product </span><span style="background-color: yellow; font-family: Verdana, sans-serif;">Propolis resulted in a consistently and
significantly (p < 0.05) lower MGMPI mean scores than the Colgate Total and
Miswak toothpastes</span><span style="font-family: Verdana, sans-serif;">.</span></div>
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<span style="font-family: Verdana, sans-serif;"><u>CONCLUSION</u>:</span><span style="font-family: Verdana, sans-serif;"> </span></div>
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<span style="font-family: Verdana, sans-serif;"><span style="background-color: yellow;">Propolis was found to be safe and effective in reducing
plaque accumulation</span> when compared to Miswak and Colgate total toothpaste.<o:p></o:p></span><br />
<span style="font-family: Verdana, sans-serif;"><br /></span>
<span style="font-family: Verdana, sans-serif;">Click <a href="http://www.slideshare.net/jflariviere/antiplaque-efficacy-of-propolis-based-herbal-toothpastea-crossover-clinical-study-52685899" target="_blank">here</a> for the complete PDF of this study.</span></div>
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BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com1tag:blogger.com,1999:blog-6405325709567335968.post-34317757978322782352015-07-18T15:23:00.000+02:002015-07-18T15:23:24.351+02:00Propolis Outperforms Herbal Extracts Against Candida Albicans<div dir="ltr" style="text-align: left;" trbidi="on">
<b><i><span style="color: purple;">An interesting study comparing the antifungal properties of numerous herbal extracts, propolis and prescription drugs against Candida albicans. This study confirms propolis is the most effective in controlling Candida albicans, even though this isn't the first time these results have been achieved. This e</span></i></b><b><i><span style="color: purple;">ncouraging </span></i></b><b><i><span style="color: purple;">news should put propolis on top of the list of every patient </span></i></b><b><i><span style="color: purple;">dealing with this opportunistic fungi.</span></i></b><br />
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<span style="font-family: Verdana, sans-serif;"><b>Comparative effect of propolis of honey bee and some herbal
extracts on Candida Albicans</b></span></div>
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<span style="font-family: Verdana, sans-serif; font-size: xx-small;"><a href="http://link.springer.com/article/10.1007%2Fs11655-015-2074-9" target="_blank">Chinese Journal of Integrative Medicine</a>, July 7 2015</span></div>
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<a href="http://1.bp.blogspot.com/-w2X5wUuCrS8/UyxDvF5x7gI/AAAAAAAAHgQ/u5ZVq5rVHD4/s1600/j_chinese_int_med.jpg" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img border="0" height="200" src="http://1.bp.blogspot.com/-w2X5wUuCrS8/UyxDvF5x7gI/AAAAAAAAHgQ/u5ZVq5rVHD4/s200/j_chinese_int_med.jpg" width="147" /></a></div>
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<u><span style="font-family: Verdana, sans-serif;">Objective</span></u></div>
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<span style="font-family: Verdana, sans-serif;">To determine the effect of propolis on Candida albicans and
to compare it with the effects of some other herbal extracts and antibiotics on
this pathogenic fungi.</span></div>
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<u><span style="font-family: Verdana, sans-serif;">Methods</span></u></div>
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<span style="font-family: Verdana, sans-serif;">The extracts of propolis, Thymus vulgaris, Caryophillium
aromaticus, Echinophora platyloba, Allium cepa and Cinnamomum zeylanicum were
prepared and the antifungi effects of the extracts were examined on Candida
albicans ATCC10231 using disc-diffusion assay and micro-broth dilution. The
minimum fungicidal concentration (MFC) and minimum inhibitory concentrations
(MIC) as well as inhibition zone were evaluated and the anti fungi effects of
herbal extracts were compared with amphotricin B and nystatin at the times of
24, 48 and 72 h. Data analysis was performed using test.</span></div>
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<u><span style="font-family: Verdana, sans-serif;">Results</span></u></div>
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<span style="font-family: Verdana, sans-serif;"><span style="background-color: yellow;">Obtained results showed that propolis extract</span> with MIC90 and
MFC equal to 39 and 65 µg/mL, respectively, <span style="background-color: yellow;">possess the highest antifungal
activity when compared with other studied extracts</span>. The extracts of Allium cepa
and Thymus vulgaris, with MFC of 169 and 137 µg/mL, respectively, showed the
lowest effects on the fungi. Also <a href="https://en.wikipedia.org/wiki/Nystatin" target="_blank">nystatin</a> and <a href="https://en.wikipedia.org/wiki/Amphotericin_B" target="_blank">amphotericin B</a> yielded better
effects on the tested fungi compared with the effects of all studied extracts
on Candida albicans.</span></div>
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<u><span style="font-family: Verdana, sans-serif;">Conclusions</span></u></div>
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<span style="font-size: 12pt;"><span style="font-family: Verdana, sans-serif;"><span style="background-color: yellow;">Propolis extract is effective in controlling Candida
albicans</span>. However, the issue requires further investigation on samples in
animals and performing toxicological examinations.</span></span></div>
<br /></div>
BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com1tag:blogger.com,1999:blog-6405325709567335968.post-49435232146428816352015-07-09T16:08:00.001+02:002015-07-09T16:08:16.208+02:00Royal Jelly Effective Against Antibiotic-Resistant Pneumonia<div dir="ltr" style="text-align: left;" trbidi="on">
<i><b><span style="color: purple;">Royal Jelly possesses many documented bioactive properties and this study found that both fresh and freeze-dried royal jelly is effective against antibiotic-resistant pneumonia. Add this to the fact that it's also a brain-booster, hormone-regulator and an anti-aging compound, not to mention that it boosts red blood cell counts, glucose tolerance and mental health!</span></b></i><br />
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<b><span style="font-family: Verdana, sans-serif;">The Lyophilization Process Maintains the Chemical and
Biological Characteristics of Royal Jelly</span></b></div>
<div class="MsoNormal">
<span style="font-family: Verdana, sans-serif;"><span style="font-size: xx-small;"><a href="http://www.hindawi.com/journals/ecam/2015/825068/" target="_blank">Evid Based Complement Alternat Med</a>. </span><span style="font-size: xx-small;">April </span><span style="font-size: xx-small;">2015</span></span></div>
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<a href="http://2.bp.blogspot.com/-TvSyZWOmq3Y/TnN2s4HJwnI/AAAAAAAACIg/mow8upxyXL4/s1600/blog_cam.jpg" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img border="0" src="http://2.bp.blogspot.com/-TvSyZWOmq3Y/TnN2s4HJwnI/AAAAAAAACIg/mow8upxyXL4/s1600/blog_cam.jpg" /></a></div>
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<span style="font-family: Verdana, sans-serif;"><br /></span></div>
<div class="MsoNormal">
<span style="font-family: Verdana, sans-serif;">The alternative use of natural products, like royal jelly
(RJ), may be an important tool for the treatment of infections caused by
antibiotic-resistant bacteria. RJ presents a large number of bioactive
substances, including antimicrobial compounds.</span></div>
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<br /></div>
<div class="MsoNormal">
<span style="font-family: Verdana, sans-serif;">In this study, we carried out the chemical characterization
of fresh and lyophilized RJ and investigated their antibacterial effects with
the purpose of evaluating if the lyophilization process maintains the chemical
and antibacterial properties of RJ. Furthermore, we evaluated the antibacterial
efficacy of the main fatty acid found in RJ, the 10-hydroxy-2-decenoic acid
(10H2DA).</span></div>
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<br /></div>
<table cellpadding="0" cellspacing="0" class="tr-caption-container" style="float: right; margin-left: 1em; text-align: right;"><tbody>
<tr><td style="text-align: center;"><a href="https://upload.wikimedia.org/wikipedia/commons/thumb/9/9f/Pneumococcus_CDC_PHIL_ID1003.jpg/240px-Pneumococcus_CDC_PHIL_ID1003.jpg" imageanchor="1" style="clear: right; margin-bottom: 1em; margin-left: auto; margin-right: auto;"><img border="0" src="https://upload.wikimedia.org/wikipedia/commons/thumb/9/9f/Pneumococcus_CDC_PHIL_ID1003.jpg/240px-Pneumococcus_CDC_PHIL_ID1003.jpg" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;"><i style="background-color: #f9f9f9; font-family: sans-serif; font-size: 12.3199996948242px; line-height: 21px;">S. pneumoniae</i><span style="background-color: #f9f9f9; font-family: sans-serif; font-size: 12.3199996948242px; line-height: 21px;"> in spinal fluid (digitally colored).</span></td></tr>
</tbody></table>
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<span style="font-family: Verdana, sans-serif;">Chromatographic profile of the RJ samples showed similar
fingerprints and the presence of 10H2DA in both samples. Furthermore, <span style="background-color: yellow;">fresh and
lyophilized RJ were effective against all bacteria evaluated</span>; that is, the
lyophilization process maintains the antibacterial activity of RJ and the
chemical field of 10H2DA. <span style="background-color: yellow;">The fatty acid 10H2DA exhibited a good antibacterial
activity against Streptococcus pneumoniae</span>.</span></div>
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<br /></div>
<span style="font-size: 12pt;"><span style="font-family: Verdana, sans-serif;">Therefore, <span style="background-color: yellow;">it may be used as an alternative and
complementary treatment for infections caused by antibiotic-resistant S.
pneumoniae</span>.</span></span></div>
BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com0tag:blogger.com,1999:blog-6405325709567335968.post-91487552627703162422015-07-03T13:38:00.004+02:002015-07-03T13:59:04.836+02:00Honey Bee Products Improve the Immune System<div dir="ltr" style="text-align: left;" trbidi="on">
<b><i><span style="color: purple;">Yet another synergistic effect from consuming bee products. </span></i></b><b><i><span style="color: purple;">This is an important update to a previous study that identified lactic acid bacteria present in honey, bee pollen and bee bread. This human trial, even though small, reveals great promise for those needing immune system support, complementing the medical community's interest in the connection between the immune system and a healthy gut.</span></i></b><br />
<b><i><span style="color: purple;"><br /></span></i></b>
<b><span style="font-size: 12pt;"><span style="font-family: Verdana, sans-serif;">Lactobacillus kunkeei YB38 from honeybee
products enhances IgA production in healthy adults</span></span></b><br />
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<span style="font-family: Verdana, sans-serif; font-size: xx-small;"><span lang="FR"><a href="http://onlinelibrary.wiley.com/doi/10.1111/jam.12889/abstract" target="_blank">J Appl Microbiol</a>.
2015 Jun 29. doi: 10.1111/jam.12889.</span></span></div>
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<a href="http://2.bp.blogspot.com/-lxmFTo2jLmw/VZZtNV_VjLI/AAAAAAAAIDU/926D2FuPGg0/s1600/blog_j_applied_microbiology.jpg" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img border="0" src="http://2.bp.blogspot.com/-lxmFTo2jLmw/VZZtNV_VjLI/AAAAAAAAIDU/926D2FuPGg0/s1600/blog_j_applied_microbiology.jpg" /></a></div>
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<span style="font-family: Verdana, sans-serif;"><u><b>AIMS</b></u>:<br />To identify lactic acid bacterial isolates that promote IgA production in
honeybee products and honeybees (Apis mellifera).<br />
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METHODS AND RESULTS</b></u>:<br />Pyrosequencing analysis of the microbiota of honeybee products and honeybees
revealed the predominance of <a href="https://en.wikipedia.org/wiki/List_of_microorganisms_used_in_food_and_beverage_preparation" target="_blank">Lactobacillus kunkeei</a> in honey, bee pollen, bee
bread, and royal jelly. L. kunkeei was isolated from bee pollen, bee bread, and
honey stomach, and its effect on IgA production was evaluated in vitro.
Heat-killed YB38 and YB83 isolates from bee pollen promoted <a href="https://en.wikipedia.org/wiki/Immunoglobulin_A" target="_blank">IgA</a> production in
mouse Peyer's Patch cells and had little mitogenic activity or effect on IL-2
production in mouse spleen cells in comparison with Listeria monocytogenes,
which does exhibit mitogen activity. A pilot study in <span style="background-color: yellow;">11 healthy adults showed
that 4-week intake of 1,000 mg/day heat-killed YB38 increased SIgA
concentrations and secretion in saliva with no adverse effects</span>.</span></div>
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<a href="https://upload.wikimedia.org/wikipedia/commons/thumb/5/59/Immunglobulin_A_as_Dimer.png/220px-Immunglobulin_A_as_Dimer.png" imageanchor="1" style="clear: right; float: right; margin-bottom: 1em; margin-left: 1em;"><img border="0" src="https://upload.wikimedia.org/wikipedia/commons/thumb/5/59/Immunglobulin_A_as_Dimer.png/220px-Immunglobulin_A_as_Dimer.png" /></a></div>
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CONCLUSION</b></u>:<br />Heat-killed L. kunkeei YB38 from bee pollen increases IgA production and <span style="background-color: yellow;">may
safely improve immune responsiveness</span>.</span><br />
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<span style="font-family: Verdana, sans-serif;"><u><b>
SIGNIFICANCE A</b></u></span><u style="font-family: Verdana, sans-serif;"><b>ND IMPACT OF THE STUDY</b></u><span style="font-family: Verdana, sans-serif;">:</span><br />
<div>
<span style="font-family: Verdana, sans-serif;"><span style="background-color: yellow;">This is the first report of microbiota analysis of royal jelly and the immune
efficacy of L. kunkeei from honeybee products in humans. </span></span><br />
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BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com0tag:blogger.com,1999:blog-6405325709567335968.post-1233739929467755942015-05-29T15:40:00.001+02:002015-05-29T19:26:36.824+02:00 Forest Honey Can Prevent Ulcers<div dir="ltr" style="text-align: left;" trbidi="on">
<span style="color: purple;"><b><i>Recognized</i></b></span><b><span style="color: purple;"><i> world wide that honey is more than a food but also medicine, this new study finds these monofloral honeys to possess specialized healing properties, in particular concerning gastric ulcers. In fact, oak and chestnut honeys inhibit enzymes which cause gout, gastritis, cardiovascular disease and peptic ulcers.</i></span></b><br />
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<span style="font-family: Verdana, sans-serif;"><b>Honey as an apitherapic product: its inhibitory effect on
urease and xanthine oxidase</b></span></div>
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<span style="font-family: Verdana, sans-serif; font-size: xx-small;"><a href="http://informahealthcare.com/doi/abs/10.3109/14756366.2015.1039532">J Enzyme Inhib Med Chem.</a> 2015 May </span></div>
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<a href="http://3.bp.blogspot.com/-N_b25280IU0/VWOchwsAUKI/AAAAAAAAIAk/4m6x2ol7PaU/s1600/blog_j_enz_inhib_med_chem.jpg" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img border="0" src="http://3.bp.blogspot.com/-N_b25280IU0/VWOchwsAUKI/AAAAAAAAIAk/4m6x2ol7PaU/s1600/blog_j_enz_inhib_med_chem.jpg" /></a></div>
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<span style="font-family: Verdana, sans-serif;">The aim of this study was to evaluate new natural inhibitor
sources for the enzymes <a href="http://en.wikipedia.org/wiki/Urease" target="_blank">urease</a> and <a href="http://en.wikipedia.org/wiki/Xanthine_oxidase" target="_blank">xanthine oxidase</a> (XO). Chestnut, oak and
polyfloral honey extracts were used to determine inhibition effects of both
enzymes.</span></div>
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<span style="font-family: Verdana, sans-serif;">In addition to investigate inhibition, the antioxidant
capacities of these honeys were determined using total phenolic content (TPC),
ferric reducing antioxidant power (FRAP), and DPPH radical scavenging activity
assays.</span></div>
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<span style="font-family: Verdana, sans-serif;"><span style="background-color: yellow;">Due to their high phenolic content, chestnut and oak honeys
are found to be a powerful source for inhibition of both enzymes. </span>Especially,
oak honeys were efficient for urease inhibition with 0.012-0.021 g/mL IC50
values, and also chestnut honeys were powerful for XO inhibition with
0.028-0.039 g/mL IC50 values.</span></div>
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<span style="font-size: 12pt;"><span style="font-family: Verdana, sans-serif;"><span style="background-color: yellow;">Regular daily consumption of these honeys can prevent
gastric ulcers deriving from <a href="http://en.wikipedia.org/wiki/Helicobacter_pylori" target="_blank">Helicobacter pylori</a> and pathological disorders</span>
mediated by reactive oxygen species.</span></span><br />
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BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com1tag:blogger.com,1999:blog-6405325709567335968.post-31613386139578722112015-05-25T19:03:00.002+02:002015-07-02T19:23:13.589+02:00Antioxidant Content in Propolis Protects Liver<div dir="ltr" style="text-align: left;" trbidi="on">
<b><i><span style="color: purple;">Propolis </span></i></b><b><i><span style="color: purple;">provides a very good quantity of </span></i></b><b><i><span style="color: purple;">antioxidants and has important protective effects on internal organs, in particular the liver. This study confirms propolis reduced hypertension by preventing blood vessels from restricting blood flow even when under the influence of a drug that induces vasorestriction. A commonly found trait in propolis is its ability to protect and heal, along with anti-inflammatory</span></i></b><b><i><span style="color: purple;"> and </span></i></b><b><i><span style="color: purple;">antimicrobial properties, it's an important adjuvant agent. </span></i></b><br />
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<b><span style="font-family: Verdana, sans-serif;">Antioxidant Effect of Ethanolic Extract of Propolis in Liver
of L-NAME Treated Rats</span></b></div>
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<span style="font-family: Verdana, sans-serif; font-size: xx-small;"><a href="http://www.advances.am.wroc.pl/strona.php?id=11&n=1743&lang=pl">Adv Clin Exp Med</a>. 2015 Mar-Apr</span></div>
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<a href="http://2.bp.blogspot.com/-pXxpHm_y0cw/VWIUPYO3uiI/AAAAAAAAH_o/p-6Mc7tJ3Bw/s1600/blog_adv_clin_exp_med_horiz.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="117" src="http://2.bp.blogspot.com/-pXxpHm_y0cw/VWIUPYO3uiI/AAAAAAAAH_o/p-6Mc7tJ3Bw/s320/blog_adv_clin_exp_med_horiz.jpg" width="320" /></a></div>
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<span style="font-family: Verdana, sans-serif;"><u>BACKGROUND</u>:</span></div>
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<span style="font-family: Verdana, sans-serif;">The blocking of nitric oxide synthase (NOS) activity may
cause <a href="http://en.wikipedia.org/wiki/Vasoconstriction">vasoconstriction</a> with formation of reactive oxygen species. Propolis is a
natural product collected from plants by honeybees. <span style="background-color: yellow;">Propolis has biological and
pharmacological properties</span>.<o:p></o:p></span></div>
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<span style="font-family: Verdana, sans-serif;"><u>OBJECTIVES</u>:</span></div>
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<span style="font-family: Verdana, sans-serif;">This study was designed to investigate the effects of
propolis on <a href="http://en.wikipedia.org/wiki/Catalase">catalase</a> (CAT) activity, <a href="http://en.wikipedia.org/wiki/Nitric_oxide">nitric oxide</a> (NO) and <a href="http://en.wikipedia.org/wiki/Malondialdehyde">malondialdehyde</a>
(MDA) levels in the liver tissues of NOS inhibited rats by <a href="http://circ.ahajournals.org/content/106/13/1729.short">Nω-Nitro-L-argininemethyl ester (L-NAME)</a>.<o:p></o:p></span></div>
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<span style="font-family: Verdana, sans-serif;"><u>MATERIAL AND METHODS</u>:</span></div>
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<span style="font-family: Verdana, sans-serif;">Rats were given a NOS inhibitor (L-NAME, 40 mg/kg, intraperitoneally)
for 15 days to provoke hypertension and propolis (200 mg/kg, by gavage) the
last 5 of the 15 days.<o:p></o:p></span></div>
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<span style="font-family: Verdana, sans-serif;"><u>RESULTS</u>:</span></div>
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<span style="font-family: Verdana, sans-serif;">Nitric oxide levels in the liver tissue of the rats given
L-NAME significantly</span><br />
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<span style="font-family: Verdana, sans-serif;"><a href="http://3.bp.blogspot.com/--cg2SRsrDDs/VWNVbakMqsI/AAAAAAAAIAI/bDxJ_uEZJOI/s1600/blog_graph_propolis_liver_LNAME.jpg" imageanchor="1" style="clear: right; float: right; margin-bottom: 1em; margin-left: 1em;"><img border="0" height="209" src="http://3.bp.blogspot.com/--cg2SRsrDDs/VWNVbakMqsI/AAAAAAAAIAI/bDxJ_uEZJOI/s320/blog_graph_propolis_liver_LNAME.jpg" width="320" /></a></span></div>
<span style="font-family: Verdana, sans-serif;"> decreased (p < 0.01). That parameter did not significantly
alter in the liver of rats treated with propolis compared to the control group.
CAT activity and MDA levels in the liver of the rats administrated L-NAME
significantly increased compared to the control group (p < 0.01). These
parameters significantly decreased in the liver of the rats given L-NAME +
propolis compared to the L-NAME group (p < 0.01).<o:p></o:p></span></div>
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<span style="font-family: Verdana, sans-serif;"><u>CONCLUSIONS</u>:</span></div>
<span style="font-size: 12pt;"><span style="font-family: Verdana, sans-serif;">The present data shows that <span style="background-color: yellow;">L-NAME in the liver may
enhance oxidative stress</span> via inhibited nitric oxide synthase. Our results also
suggest that <span style="background-color: yellow;">this effect is suppressed by the antioxidant properties of
propolis in the liver</span> tissue of NOS inhibited rats.</span></span><br />
<span style="font-size: 12pt;"><span style="font-family: Verdana, sans-serif;"><br /></span></span>
<span style="font-size: 12pt;"><span style="font-family: Verdana, sans-serif;">Click here for the <a href="http://www.slideshare.net/jflariviere/antioxidant-effect-of-propolis-extract-on-liver" target="_blank">complete study</a>.</span></span><br />
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BeeHealthyFarmshttp://www.blogger.com/profile/13157786053279032910noreply@blogger.com1