Monday, April 30, 2012

Bee Propolis Extract Heals Wounds

An added advantage to using a propolis extract is that it seals the wound with a thin film of the resinous substance, creating a protective adhesive bandage. This is precisely why I carry a bottle with me, especially when doing physical labor and getting my share of cuts and scratches...

Propolis Standardized Extract (EPP-AF®), an Innovative Chemically and Biologically Reproducible Pharmaceutical Compound for Treating Wounds
Int J BiolSci 2012, April
The aim of this study was to develop a formulation, containing the propolis standardized extract (EPP-AF®), which can assist in the healing of skin lesions.

To achieve this objective the antimicrobial activity and chemical composition of the propolis extract was determined. The final product was subjected to in vitro and in vivo pre-clinical evaluation. The broth macrodilution method was used to determine the antimicrobial activity of the extracts and formulations against the microorganisms most commonly found in burns, Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, Staphylococcus aureus and Staphylococcus epidermidis.

Wistar rats with puncture wounded skin were used to evaluate the wound healing properties of propolis. The results of chemical and biological characterization demonstrated the batch-to-batch reproducibility of the standardized extract which is an unprecedented result.

The antimicrobial and wound healing activity of the pharmaceutical studied showed the best results when samples contain 3.6% propolis, suggesting that this is the most promising composition. 

Thermal injury is a major cause of morbidity and impaired quality of life in many areas of the world. Each year in The United States of America, more than 1.25 million people suffer burns. It has been estimated that 75% of deaths following burn injuries are related to infection…

In addition to the need for more convenient wound dressing and pharmaceuticals, it is also important to discover therapeutic agents that are more effective against microbial infections frequently related with burns...

Several studies have been published on the many different existing propolis extracts, both with regard to their biological activities and safety... 


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