the unrelenting power of propolis, proving once again its anti-carcinogenic properties...
Propolis is
a resinous product collected by honey bees. It was also reported that propolis
has a wide variety of biological actions, including antimicrobial activity and
antioxidant, anti-inflammatory, and suppressive effects of dioxin toxicity activities.
Comparison
of Effects of the Ethanolic Extracts of Brazilian Propolis on Human Leukemic
Cells As Assessed with the MTT Assay
Evidence-BasedComplementary and Alternative Medicine, Volume 2012
Propolis is
a resinous product collected by honey bees. It was also reported that propolis
has a wide variety of biological actions, including antimicrobial activity and
antioxidant, anti-inflammatory, and suppressive effects of dioxin toxicity activities.
The aim of
this study was to compare the in vitro cytotoxic activities of green propolis
(G12) and red propolis (G13) in human leukemia cells. These cells were
incubated with different concentrations of propolis and 48 hours after the IC50
was calculated for each cell.
The results
showed that the red propolis has cytotoxic effect in vitro higher than green
propolis. Red propolis was showed to be cytostatic in K562 cells and caused the
same amount of apoptosis as its control Gleevec.
In
conclusion, these results showed that red propolis is more cytotoxic than the
green propolis in a variety of human cell lines of leukemia. Red propolis may
contain drugs capable of inhibiting cancer cell growth. Therefore, further
isolation of respective chemical ingredients from the red propolis (G13) for
identification of the activities is necessary.
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