Consuming several bee products provides a synergistic effect, whereby the benefits of each are enhanced when taken ensemble. This has been established in previous studies and this new study reaffirms that Apitherapy protects and prevents even neurodegenerative illnesses...
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monoamine oxidase (MAO) inhibition by chestnut honey, pollen and propolis
J Enzyme Inhib Med Chem, 2013 Oct 24
Abstract
Monoamine oxidase (MAO) inhibitors are generally used in the treatment of
depressive disorders and some neurodegenerative illnesses, such as Parkinson's
disease and Alzheimer's disease.
The aim of
this preliminary study was to investigate the MAO [MAO (E.C.1.4.3.4)]
inhibiting effect of various apitherapeutic products, such as chestnut honey,
pollen and propolis.
Extracts'
MAO inhibition was measured using peroxidase-linked spectrophotometric assay in
enzyme isolated from rat liver microsomes, and the values are expressed as the
inhibition concentration (IC50) causing 50% inhibition of MAO. The antioxidant
activity of the bee products was also determined in terms of total phenolic
content (TPC) and ferric reducing/antioxidant power in aquatic extracts.
All samples
exhibited substantial inhibition of MAO, propolis having the highest.
Inhibition was related to samples' TPCs and antioxidant capacities.
These
results show that bee products possess a sedative effect and may be effective
in protecting humans against depression and similar diseases.
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