Thyme Honey Validated to Possess Wound Healing Capacities

Ironically, this has been proven and practiced in France at the Central Hospital Unit in Limoges. Prof. Descottes conducted numerous double-blind studies that confirmed Thyme Honey's ability to heal wounds better and faster than pharmaceutically prescribed treatments as well as other monofloral honeys. He also proved that other honeys can heal wounds too, but that Thyme honey was the best...

Honey-induced macrophage stimulation: AP-1 and NF-κB activation and cytokine production are unrelated to LPS content of honey

Int Immunopharmacol, 2013 Oct 11

Honey is well known for its wound healing properties although the cellular and molecular mechanisms underlying honey-stimulated healing process are still poorly understood. The present study was intended to characterize the stimulation of Raw 264.7 murine macrophages in response to thyme honey.

Honey induces significant increase in PGE2 production, and overexpression of both COX-2 and TNF-α (p < 0.001). This increase was concomitant with overexpression and activation of the AP-1 and NF-κB transcription factor subunits. The small LPS content of honey could not, by itself, account for the reported observations.

These results suggest that other thyme honey components participate in the stimulation of cytokine production required for effective wound healing process.