A fantastic study revealing the "synergistic effects" of an Apitherapy diet, combining multiple bee products enhances the effects of each individual product thereby boosting the overall results. This study reaffirms the previous results which identified the detoxing effects of honey and propolis on liver and kidneys.
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Effect of Apitherapy Formulations against Carbon
Tetrachloride-Induced Toxicity in Wistar Rats after Three Weeks of Treatment
Molecules 2014, 19(9), 13374-13
The human body is exposed nowadays to increasing attacks by
toxic compounds in polluted air, industrially processed foods, alcohol and drug
consumption that increase liver toxicity, leading to more and more severe cases
of hepatic disorders. The present paper aims to evaluate the influence of the
apitherapy diet in Wistar rats with carbon tetrachloride-induced
hepatotoxicity, by analyzing the biochemical determinations (enzymatic, lipid
and protein profiles, coagulation parameters, minerals, blood count parameters,
bilirubin levels) and histopathological changes at the level of liver, spleen
and pancreas.
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| Liver samples |
The experiment was carried out on six groups of male Wistar
rats. Hepatic lesions were induced by intraperitoneal injection of carbon
tetrachloride (dissolved in paraffin oil, 10% solution). Two mL per 100 g were
administered, every 2 days, for 2 weeks. Hepatoprotection was achieved with two
apitherapy diet formulations containing honey, pollen, propolis, Apilarnil,
with/without royal jelly.
 |
| Spleen samples |
Biochemical results reveal that the two apitherapy diet
formulations have a positive effect on improving the enzymatic, lipid, and
protein profiles, coagulation, mineral and blood count parameters and bilirubin
levels. The histopathological results demonstrate the benefits of the two apitherapy
diet formulations on reducing toxicity at the level of liver, spleen and
pancreas in laboratory animals.
 |
| Pancreas samples |
To download the full whitepaper, click here.
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