Propolis has naturally-occurring protective powers which work for all creatures - bees, fish even humans! This study identifies that these properties in propolis protect against a toxic pesticide, Chlorpyrifos, known to have negative developmental consequences in fetuses, risk of lung cancer in farmworkers and increased autoimmune disorders...
The findings of this study demonstrated that CPF
had a negative effect on the haematological parameters and the antioxidant
enzyme activities of the fish; this toxic effect was neutralised by the
administration of propolis. The present results suggest that propolis can be
effective in the protection of CPF-induced toxicity in fish.
Protective
Role of Propolis in Chlorpyrifos-Induced Changes in the Haematological
Parameters and the Oxidative/Antioxidative Status of Cyprinus carpio carpio
Food ChemToxicol, 2012 May 22
The protective
effect of propolis on haematological parameters and antioxidant status were
evaluated in the blood and various tissues of carp exposed to chlorpyrifos
(CPF).
The fish
were exposed to sublethal concentrations of CPF (0.040 and 0.080mg/L) for
10days, and propolis (10mg per kg of fish weight) was simultaneously
administered. Samples of the blood and tissue (liver, kidney, and gill) were
collected at the end of the experiment and analysed for their
oxidant-antioxidant status, including the malondialdehyde (MDA) levels, and the
superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px)
activity. The samples were also measured for changes in the haematological
parameters, such as the red blood cell (RBC) and white blood cell (WBC) counts,
the haemoglobin concentration (Hb), the haematocrit (Ht) level, and the
erythrocyte indices: the mean corpuscular volume (MCV), the mean corpuscular
haemoglobin (MCH) and the mean corpuscular haemoglobin concentration (MCHC).
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