A really good study confirming the beneficial effects of propolis for chronic sinus ailments such as rhinosinusitis. Another interesting point is the consistent effect of its healing, protective properties on injuries, especially in mucous linings of the body.
Chronic Rhinosinusitis Healed with Propolis
INTRODUCTION:
Mechanical trauma to the nasal mucosa
increases the risk of synechia formation, especially after chronic
rhinosinusitis and nasal surgeries.
OBJECTIVE:
This study was carried to assess the effect
of propolis administration in healing injured nasal mucosa in rats.
METHODS:
We randomly divided eighteen rats into
three equal experimental groups: (1) non-treated group; (2) gum tragacanth
(suspending agent for propolis) treated group; and (3) propolis treated group.
The non-treated group received no treatment for 15 days. The second group
received gum tragacanth administration (5 ml/kg, orally) once daily for 15
days. The third group received propolis suspension orally at a dose of 100
mg/kg once daily for 15 days. At the beginning of this study, we induced
unilateral mechanical nasal trauma on the right nasal mucosa of all rats in the
three groups using a brushing technique. A pathologist stained tissue samples
using hematoxylin and examined eosin by using a light microscope.
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| Photomicrographs of (1) non-treated, (2) gum (3) propolis |
RESULTS:
The severity of inflammation was milder
with the absence of ulcerations in the propolis treated group compared with the
non-treated and gum tragacanth groups. Goblet cell and ciliated cell loss was
substantially lower in patients treated with propolis compared with groups
without treatment and those treated with gum tragacanth.
CONCLUSION:
Propolis decreased inflammation and
enhanced healing of wounds of the nasal mucosa in rats.
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