Propolis, with over 300 compounds identified, is a very rich source of antioxidants stemming from its many phenolic sources. This study confirms the importance of one particular component, Pinobanksin-3-acetate, harvested by bees from Poplar trees in France...
The purpose
of this study was to evaluate the AO and anti-AGEs potential of a propolis
batch, then to identify the main compounds responsible for these effects. In
vivo, protein glycation and oxidative stress are closely related. Thus AO and
antiglycation activities were respectively evaluated using both DPPH and ORAC
assays as well as a newly developed automated anti-AGEs test.
Chemical
composition, antioxidant and anti-AGEs activities of a French poplar type
propolis
J Agric Food Chem, 2014 Jan
Accumulation
in tissues and serum of advanced glycation end-products (AGEs) plays an
important role in pathologies such as Alzheimer's disease or, in the event of
complications of diabetes, atherosclerosis or renal failure. Therefore there is
a potential therapeutic interest in compounds able to lower intra and
extracellular levels of AGEs. Among them, natural antioxidants (AO) with true
anti-AGEs capabilities would represent good candidates for development.
The purpose
of this study was to evaluate the AO and anti-AGEs potential of a propolis
batch, then to identify the main compounds responsible for these effects. In
vivo, protein glycation and oxidative stress are closely related. Thus AO and
antiglycation activities were respectively evaluated using both DPPH and ORAC
assays as well as a newly developed automated anti-AGEs test.
Several
propolis extracts exhibited very good AO and anti-AGEs activities and a
bio-guided fractionation allowed us to identify pinobanksin-3-acetate as the
most active component.
Congratulations on the blog!
ReplyDeleteReally it is very interesting and contains lots of important information for the amentes bees.
Hug!
Paul Romero.
Meliponary Braz.
Brazil.